Program Officer, Chemistry Pharmacology Physiology Branch (CPP)

The National Institute on Drug Abuse (NIDA), Division of Neuroscience and Behavior (DNB), Chemistry Pharmacology Physiology Branch (CPP) is seeking applicants for the position of Program Officer to develop a grant portfolio in the rapidly growing field of chemistry and pharmacology of drugs of abuse. The Branch supports all research related to the chemistry and pharmacology of drugs of abuse including, the structural dynamics of receptors, computationally-based drug design, intracellular signaling mechanisms, early drug discovery of treatments for addiction, natural product chemistry and innovative mechanisms of drug delivery. The Program Officer is expected to develop and oversee portfolios in research that takes advantage of innovative approaches that are emerging in this field. This includes new tools and technology that allow for rapid determination of the atomic structure of receptors and their dynamic properties, including binding, signaling and trafficking. Along with this, recent developments in the application of computational tools, machine learning methods, and artificial intelligence are facilitating the rapid identification of druggable targets and the discovery of new ligands with which to modulate the interaction and function of these targets. In addition to receptor pharmacology, advances in the fields of genomics, transcriptomics, proteomics, peptidomics, lipidomics, metabolomics, signaling molecules and their interaction networks could prove transformative in understanding neural communication and in treating substance use disorders.

The position involves working with current grantees, creating new research initiatives that guide the future of research in this area, serving as a NIDA representative in the area of chemistry and pharmacology at conferences, and organizing conferences and workshops to advance the research through the facilitation of collaborations. Applicants should have expertise and experience in chemistry, drug design, biophysical and computational approaches, biochemical and neurobiological mechanisms of substance use disorders. Applicants should also have a doctoral degree in one of the sciences underlying these research areas (for example, chemistry, biophysics, biomedical technologies, computational biology, etc.). Familiarity with NIH grant writing and review process would also be useful.

All applicants should include a cover letter indicating interest in the position within DNB/NIDA.

For additional information about this position, please contact Dr. Sam Ananthan at