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In addition, HJ Optronics is the only company that offers customization to our needs, which includes individual cooling systems, huge variety of wavelengths, and their lasers are among the most powerful lasers found in the optogenetics market. Additionally, they offer the possibility to have multiple laser wavelengths within one single unit, which is a plus compared to other companies, where items need to be purchased individually.
As part of its service to the NIH community, the NIF must provide specialized equipment for shared use to a broad spectrum of researchers with various levels of expertise from Neuroscience fields.
This laser is of high importance in our research as it will enable us to stimulate multiple sites across the brain of mammals and to test the causal link across multiple brain networks. Similarly, our approach can be readily adopted in a variety of fMRI studies that require (1) sequential cell-type-specific stimulation on multiple sites for mapping functional cortico-cortical or subcortical networks, (2) temporally controlled stimulation on multiple sites for investigating interregional functional coupling balances, (3) an in situ subject-specific stimulation design defined by anatomical or functional imaging, and (4) simultaneous functional mapping of cortical areas through optical imaging and cortical-subcortical regions by fMRI.
The purchase of the laser not only benefits fMRI projects, but it also provides the means for optogenetic manipulation in combination with other methods allowing whole-brain dynamics. For instance, combining optogenetics with EEG/ECoG in which causally stimulating a defined cortical circuit will offer an opportunity to arrive at a hierarchical model of brain hierarchical communication.
Changchun New Industries Optoelectronics Technology Co., Ltd (CNI optical), Model: Muti-channel (FC-MS-CH) laser system. Type: 3 combined wavelengths FC-470/589/635, Components: Fiber core diameter: 200 um, Output power: 1W, Multimode Fiber, Integrated cooling method, RS232.
Salient Characteristics:
- Powerful laser system for optogenetics ( ~ 1W).
- Wavelengths suitable to our needs. Other companies such as Thorlabs and Optomechanis offer multiple wavelengths that are not compatible to our needs.
- This system can accommodate the 3 wavelengths we need for our research: 470 nm, 589 nm, and 635 nm.
- The laser can individually control the laser output of each channel or combine multiple channels at the same time.
- Built-in driver for easy operation. Light can be delivered using TTL modulation or CW, or any analog input.
- TTL modulation can be adjusted to different frequencies 1 Hz,-30kHz, perfectly suitable to optogenetically stimulate neurons.
- Comes with SMA connectors, which are compatible with our multimode fibers.
- Operates at low temperature 10 ~35 compared to other laser systems as it is integrated with cooling method.
- Dimensions of this system is around 330 x 291 x 156 (mm).
- The products offer by this company are certified by FDA.
Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.
All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.
All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.