75N95020Q00234

Submitted by pluggern on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
G-Protein Coupled Receptor (GPCR) Peptide Ligand Library
Contracting Office
National Institute on Drug Abuse (NIDA)

Contact Points

Primary Contract Specialist

Kevin
Alvarez
kevin.alvarez@nih.gov
NAICS Code Number
325414
NCATS is in need of G-Protein Coupled Receptor (GPCR) Peptide Ligand Library to enable high-throughput screening of an pain-related G protein coupled receptors (GPCRs) targets, e.g., GPR151. This library will be used to detect the agonists or antagonists of those pain-related GPCRs. This peptide library will also be used in several other NCATS drug targets of interest, e.g., GPR17 and EPO receptor, and so meets several stated needs.
Small Business Size Standard
1,250 employees
FPDS Classification Code
6550
Estimated Period of Performance
N/A
Delivery of Goods
2-4 weeks after receipt of order
Competition Status
Non-Competitive
Vendor Name
Phoenix Pharmaceuticals
Vendor Address
330 Beach Rd
Burlingame, CA 94010
Single-Sole Source Determination
I hereby determine that the item or service listed herein is available from only one source and competition is precluded for the reasons that there are no substitutes or alternatives available.
Background/Description of Requirement

The National Center for Advancing Translational Sciences (NCATS) is a part of the National Institutes of Health (NIH), which mission it is to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions.

As a part of HEAL (Helping to End Addiction Long-term) Initiative launched by NIH this year, NCATS is currently pursuing screening of new targets of Pain and Addiction. GPR151 is the new targets for pain and addiction and NCATS would like to discover peptide modulators against the receptor. To fulfill this goal,  NCATS is in need of this peptide library to enable these novel drug discovery efforts. NCATS is in need of G-Protein Coupled Receptor (GPCR) Peptide Ligand Library to enable high-throughput screening of an pain-related  G protein coupled receptors (GPCRs) targets, e.g., GPR151. This library will be used to detect the agonists or antagonists of those pain-related GPCRs. This peptide library will also be used in several other NCATS drug targets of interest, e.g., GPR17 and EPO receptor, and so meets several stated needs.

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.