DA-20-004141

Submitted by pluggern on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Compounds for NCATS ETB probe website project
Contracting Office
National Center for Advancing Translational Sciences (NCATS)

Contact Points

Primary Contract Specialist

Anna
Chiang
anna.chiang@nih.gov

Secondary Contracting Officer

Anna
Chiang
anna.chiang@nih.gov
NAICS Code Number
325414
This requisition is to acquire compounds needed to expand the NCATS ETB probe inventory. The compounds/probes will be offered to collaborators and scientists interested in testing their hypothesis against the probes ETB made. The compounds will be available through the ETB probe website.
Small Business Size Standard
1000
Delivery of Goods
One-time delivery within 30 days ARO.
Competition Status
Brand Name Only
Vendor Name
Sigma-Aldrich (Millipore)
Address
3050 Spruce Street, Saint Louis, MO 63103
Single-Sole Source Determination
The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted specifically producing no other sources of supply or service capable of achieving this Government requirement.

Salient characteristics:
• Purity levels must be between 88 and 98%
• Must include product data
• Must include SDF file of structures
• Each vial must be properly barcoded
Background/Description of Requirement

Small molecule chemical compounds, which can be used to test or “probe” the effects of increasing or decreasing the activity of a biological target in cells or animals, are some of the most powerful tools for target validation, which is the process of demonstrating that engaging a target provides meaningful therapeutic benefit. Probes enable researchers to investigate protein and cell functions and biological processes. If appropriate, probes can be optimized to become potential drug candidates.

Generating these chemical probes requires specialized expertise and facilities, and NCATS has built world-leading collaborative services to meet these needs. The program has created over a hundred probes and it is willing to share with the general public. To this end, we are developing a website where a small portion of one or all probes will be readily available for anyone who wants to test a hypothesis. NCATS ETB does not have every probe in stock. This requisition is to purchase the compounds mentioned below to fulfill our in-house stock availability of these compounds.  

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.