NIH-NINDS-21-011531- Notice of Intent

Submitted by patelsnv on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Second-generation Multi-Fiber Photometry System
Contracting Office
National Institute of Neurological Disorders and Stroke (NINDS)

Contact Points

Primary Contract Specialist

Valerie
Gregorio
valerie.gregorio@nih.gov
NAICS Code Number
541330
Engineering Services
Small Business Size Standard
$16.5 million
FPDS Classification Code
N/A
Estimated Period of Performance
N/A
Delivery of Goods
BLDG 35 RM 3B1010
Set-Aside Status
Not Set Aside
Competition Status
Brand Name Only
Vendor Name
Sage Scientific LLC DBA Neurophotometrics Ltd.
Address
10449 Roselle ST STE 1
San Diego, California 92121
United States
Single-Sole Source Determination
Our laboratory is acquiring a multi-fiber photometry system for use with in-vivo imaging experiments. The unique characteristics of the FP3002 fiber photometry system from Neurophotometrics makes it the ideal photometry system to meet the experimental needs of the lab. First, the FP3002 system is the only available photometry system that allows for simultaneous recordings from multiple different regions of interest (this can be up to 8 different brain regions in the same animal, one brain region from up to 8 different animals, or any combination of the two). Moreover, these simultaneous recordings can be in multiple fluorescent channels (including an isobestic control channel and two emission channels in red and green). This is especially important since many of the labs experiments will require the use of all three channels to simultaneously monitor various biomarkers. Additionally, the FP3002 system offers stable LED’s for image acquisition (stability within 1 nW), while maintaining rapid acquisition rates (up to 200 Hz). Finally, the FP3002 system is the only available fiber photometry system that offers integration of two fiber-coupled lasers for optogenetic stimulation. This setup allows the lab to conduct experiments that utilize the rapid kinetics of optogenetics to activate or inhibit certain neuronal cell types, while simultaneously recording fiber photometry activity. Furthermore, FP3002 system interfaces with opensource software, Bonsai, which, in will allow the LCSMS to customize both acquisition and analysis programs for experimental use. Importantly, the FP3002 system is offered as a complete “plug and play” system, with no assembly, or further components necessary to perform the above specified functions. These exclusive characteristics of the FP3002 fiber photometry system from Neurophotometrics makes it the ideal photometry system to meet the experimental needs of the lab.
Background/Description of Requirement

LCSMS requires a state of the art, adaptable fiber photometry system that allows for both optogenetic stimulation and simulatenous recordings from multiple brain regions.

 

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.