NIH-NINDS - 22-012130 - Notice of Intent

Submitted by patelsnv on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Purchase of a Quantbio qPCR Instrument for the Neuro Therapeutics Development Unit, NTDU
Contracting Office
National Institute of Neurological Disorders and Stroke (NINDS)

Contact Points

Primary Contract Specialist

Valerie
Gregorio
valerie.gregorio@nih.gov
NAICS Code Number
334516
Analytical Laboratory Instrument Manufacturing
Small Business Size Standard
1,000 employees
FPDS Classification Code
N/A
Estimated Period of Performance
N/A
Delivery of Goods
BLDG 10 RM 7C214
Set-Aside Status
Not Set Aside
Competition Status
Brand Name Only
Vendor Name
VWR
Address
Radnor Corporate Center
Building One, Suite 200
100 Matsonford Road
Radnor, PA 19087-8660
Single-Sole Source Determination
Per the program areas researched the Quantabio Q qPCR instrument meets the specific needs of the NTDU for the quick and accurate completion of protein thermal shift assays for drug discovery and VWR is the supplier that provides the instrument for the most value.
Background/Description of Requirement

The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the NIH, and conducts research into the causes, treatment, and prevention of neurological disorders and stroke. The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease.

The NTDU utilizes a variety of techniquess to conduct translational research to develop therapies for neurological diseases. One of these techniques is the protein thermal shift assay which assesses the binding affinity of protein/drug combinations that may have therapeutic relevance.  One way to perform this assay is with a qPCR instrument that also has special software that can determine the protein/drug binding affinity.  The Quantabio Q qPCR instrument is a small machine that has the necessary capabilities to assess and quantify protein/drug interventions at a throughput that will allow the NTDU to test a variety of drugs against target proteins that have relevance in the treatment of a variety of neurological diseases

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.