NIH-NINDS-POTS 24-000246 - Notice of Intent

Submitted by patelsnv on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Objective Z-Piezo Stage
Contracting Office
National Institute of Neurological Disorders and Stroke (NINDS)

Contact Points

Primary Contract Specialist

Elaine
Estrella
elaine.estrella@nih.gov
NAICS Code Number
334516
Analytical Laboratory Instrument Manufacturing
Small Business Size Standard
1,000 Employees
FPDS Classification Code
N/A
Estimated Period of Performance
N/A
Delivery of Goods
BLDG 35 RM 1C-1006
Set-Aside Status
Not Set Aside
Competition Status
Brand Name or Equal
Rationale/ Salient Characteristics
The NINDS SNMU requires the Bruker Objective Z-Piezo Stage, a fast piezoelectric objective positioner for imaging the entire volume of individual neurons and circuitries, which will interface with the current Bruker Ultima 2Pplus two-photon microscope (NIH decal no.: 02211037) and Investigator Plus two-photon microscope (NIH decal no.: 02211035), must have the following features:
 Bruker supports this application with the objective Z-piezo stage, a fast piezoelectric objective positioner. Synchronizing resonant galvo imaging to Z-piezo steps in Bruker’s Prairie View acquisition software supports sufficient speeds for volume scanning.
 In the exemplary volume scanning data featured here, four 441 × 512-pixel imaging planes were separated by 20 μm and imaged sequentially at a stack rate of 5 Hz in an imaging session. Even faster rates can be achieved with other settings.
 To take advantage of multiphoton technology, which allows imaging down to 1mm within a sample, Bruker offers 0.25 mm, 0.4 mm, and 1 mm with 0.05 μm step size working distance Z-piezo stages. The piezo can be used with variety of objectives offered commercially.
 The operation of the piezo is controlled in Bruker’s proprietary software, Prairie View. With this system, acquisition that is calibrated, fast, and bidirectional is supported. Additional time between frames can be set to give the Z-piezo stage time to settle before the acquisition of the subsequent frame. To improve positioning accuracy during data acquisition, a calibration procedure can be performed at a single click.
 The objective Z-piezo stage is an add-on module that consists of a piezo stage, a set of objective adapters, and an electronics control box. The module can be installed easily by the user. Additionally, remote support or an onsite visit is provided.
The unique features of Objective Z-Piezo Stage from Bruker Nano, Inc. will allow the lab to take synchronizing resonant galvo imaging to Z-piezo steps in Bruker’s Prairie View acquisition software supports sufficient speeds for volume scanning on mice cortex in vivo respectively.
Single-Sole Source Determination
Determined that the Objective Z-Piezo Stage listed herein is available from only one source, and competition is precluded for the reasons indicated below. There are no substitutes available. The estimated cost of the required item or service is $18220.00 and is required to be delivered by 30 - 90 Days ARO.
- This acquisition is restricted to Bruker Nano, Inc.
- Because of the urgency of this requirement, only one source will be solicited

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.