- Substance Abuse Center for Behavioral Health Statistics and Quality. Results from the 2016 National Survey on Drug Use and Health: Detailed Tables. SAMHSA. https://www.samhsa.gov/data/sites/default/files/NSDUH-DetTabs-2016/NSDUH-DetTabs-2016.htm. Published September 7, 2017. Accessed March 7, 2018.
- Cicero, T.J.; Ellis, M.S.; and Surratt, H.L. Effect of abuse-deterrent formulation of OxyContin. N Engl J Med 367(2):187–189, 2012.
- National Institute on Drug Abuse. Epidemiologic Trends in Drug Abuse, in Proceedings of the Community Epidemiology Work Group, January 2012. Bethesda, MD: National Institute on Drug Abuse, 66.
- Pollini, R.A.; Banta-Green, C.J.; Cuevas-Mota, J.; Metzner, M.; Teshale, E.; and Garfein, R.S. Problematic use of prescription-type opioids prior to heroin use among young heroin injectors. Subst Abuse Rehabil 2(1):173–180, 2011.
- Lankenau, S.E.; Teti, M.; Silva, K.; Jackson Bloom, J.; Harocopos, A.; and Treese, M. Initiation into prescription opioid misuse amongst young injection drug users.Int J Drug Policy 23(1):37–44, 2012.
- Johnston, L.D.; Meich, R.A., O’Malley, P.M.; Bachman, J.G.; Schulenberg, J.E.; and Patrick, M.E. Monitoring the Future National Results on Adolescent Drug Use: 1975-2017. Overview, Key Findings on Adolescent Drug Use. Ann Arbor: Institute for Social Research, The University of Michigan. Available at: www.monitoringthefuture.org
- American Psychiatric Association. Substance-Related and Addictive Disorders, in Diagnostic and Statistical Manual of Mental Disorders, 5th Edition. Washington, DC: American Psychiatric Publishing, 540–550, 2013.
- National Institute on Drug Abuse, Community Epidemiology Working Group. Epidemiologic Trends in Drug Abuse, in Proceedings of the Community Epidemiology Work Group, January 2014, Bethesda, MD: National Institute on Drug Abuse. In preparation.
- Waldhoer, M.; Bartlett, S.E.; and Whistler, J.L. Opioid receptors. Annu Rev Biochem 73: 953–990, 2004.
- Johnson, S.W.; and North, R.A. Opioids excite dopamine neurons by hyperpolarization of local interneurons. J Neurosci 12(2):483–488, 1992.
- Goldstein, A. Heroin addiction: neurobiology, pharmacology, and policy. J Psychoactive Drugs 23(2):123–133, 1991.
- National Library of Medicine. Cerebral hypoxia. Available at: https://medlineplus.gov/ency/article/001435.htm. Updated March 5, 2018. Accessed March 17, 2018.
- Wang, X.; Li, B.; Zhou, X.; Liao, Y.; Tang, J.; Liu, T.; Hu, D.; and Hao, W. Changes in brain gray matter in abstinent heroin addicts. Drug Alcohol Depend 126(3):304–308, 2012.
- Ignar, D.M.; and Kuhn, C.M. Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat. J Pharmacol Exp Ther 255(3):1287–1295, 1990.
- Kreek, M.J.; Ragunath, J.; Plevy, S.; Hamer, D.; Schneider, B.; and Hartman, N. ACTH, cortisol and beta-endorphin response to metyrapone testing during chronic methadone maintenance treatment in humans. Neuropeptides 5(1-3):277–278, 1984.
- Li, W.; Li, Q.; Zhu, J.; Qin, Y.; Zheng, Y.; Chang, H.; Zhang, D.; Wang, H.; Wang, L.; Wang, Y.; Wang, W. White matter impairment in chronic heroin dependence: a quantitative DTI study. Brain Res 1531:58-64, 2013.
- Qiu, Y.; Jiang, G.; Su, H.; Lv, X.; Zhang, X.; Tian, J.; Zhou, F. Progressive white matter microstructure damage in male chronic heroin dependent individuals: a DTI and TBSS study. PLoS One 8(5):e63212, 2013.
- Liu, J.; Qin, W.; Yuan, K.; Li, J.; Wang, W.; Li, Q.; Wang, Y.; Sun, J.; von Deneen, K.M.; Liu, Y.; Tian, J. Interaction between dysfunctional connectivity at rest and heroin cues-induced brain responses in male abstinent heroin-dependent individuals. PLoS One 6(10):e23098, 2011.
- Kreek, M.J.; Levran, O.; Reed, B.; Schlussman, S.D.; Zhou, Y.; and Butelman, E.R. Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics. J Clin Invest 122(10):3387–3393, 2012.
- Chen, L.H.; Hedegaard, H.; and Warner, M. QuickStats: Number of Deaths from Poisoning, Drug Poisoning, and Drug Poisoning Involving Opioid Analgesics - United States, 1999–2010. Morbidity and Mortality Weekly Report 234, 2013.
- Magiorkinis, G.; Sypsa, V.; Magiorkinis, E.; Paraskevis, D.; Katsoulidou, A.; Belshaw, R.; Fraser, C.; Pybus, O.G.; and Hatzakis, A. Integrating phylodynamics and epidemiology to estimate transmission diversity in viral epidemics. PLoS Comput Biol 9(1):e1002876, 2013.
- Centers for Disease Control and Prevention. Surveillance for Viral Hepatitis - United States, 2014. Atlanta, GA: Centers for Disease Control and Prevention, 2014.
- Jones, H.E.; Kaltenbach, K.; Heil, S.H.; Stine, S.M.; Coyle, M.G.; Arria, A.M.; O’Grady, K.E.; Selby, P.; Martin, P.R.; and Fischer, G. Neonatal abstinence syndrome after methadone or buprenorphine exposure. N Engl J Med 363(24):2320–2331, 2010.
- Kraft, W.K.; Dysart, K.; Greenspan, J.S.; Gibson, E.; Kaltenbach, K.; and Ehrlich, M.E. Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome. Addiction 106(3):574–580, 2010.
- Lund, I.O.; Fischer, G.; Welle-Strand, G.K.; O’Grady, K.E.; Debelak, K.; Morrone, W.R.; Jones, H.E. A comparison of buprenorphine + naloxone to buprenorphine and methadone in the treatment of opioid dependence during pregnancy: maternal and neonatal outcomes. Subst Abuse 7:61–74, 2013.
- Kraft WK, Adeniyi-Jones SC, Chervoneva I, et al. Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome. N Engl J Med. 376(24):2341-2348, 2017.
- Boyer, E.W. Management of opioid analgesic overdose. N Engl J Med 367(2):146–155, 2012.
- Coffin, P.O.; and Sullivan, S.D. Cost-effectiveness of distributing naloxone to heroin users for lay overdose reversal. Ann Intern Med 158(1):1–9, 2013.
- U.S. Food and Drug Administration. FDA approves higher dosage of naloxone nasal spray to treat opioid overdose. FDA News Release April 30, 2021
- U.S. Food and Drug Administration. FDA approves new hand-held auto-injector to reverse opioid overdose. FDA News Release. April 3, 2014. Available at https://wayback.archive-it.org/7993/20170112032835/http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm391465.htm.