National Institute on Drug Abuse NIDA is the lead federal agency supporting scientific research on drug use and its consequences. Learn More About NIDA Image News Release NIH scientists identify new brain mechanism involved in impulsive cocaine-seeking in rats Muscarinic acetylcholine M2 receptors regulate lateral habenula neuron activity and control cocaine seeking behavior Image Nora's Blog Investing in Prevention Makes Good Financial Sense Primary prevention is relatively inexpensive compared to the costs of addiction Image News Release Tobacco smoking rates are decreasing in people with major depression and substance use disorder Despite decline, smoking cessation efforts still critical for people with substance use or other psychiatric disorders Image News Release Drug use severity in adolescence affects substance use disorder risk in adulthood Screening for substance use disorder in teens may predict adult prescription drug use and misuse and prevent overdose NIDA Points of Interest Image About NIDA Advancing the science on the causes, consequences, and treatment of drug use. Image Director's Page Nora D. Volkow, M.D., became Director of NIDA in May 2003. Image Grants & Funding Research grants, contracts, and supplements related to drug use and addiction. Image NIDAMED: Clinical Resources Substance use screening tools, guidelines, and other resources. Image Research & Training Programs to support research training from high school through tenure. Image NIDA Research Programs & Activities Learn about NIDA-supported research and cross-agency research activities on drug use and addiction. Image Infographic Medications for Opioid Overdose, Withdrawal, & Addiction Explore the different types of medications prescribed for opioid overdose, withdrawal, and addiction Featured Initiatives HEAL Initiative HIV Research Program (HRP) Clinical Trials Network ABCD Study - Adolescent Brain Racial Equity Initative Latest from NIDA News Release NIH scientists identify new brain mechanism involved in impulsive cocaine-seeking in rats Nora's Blog Investing in Prevention Makes Good Financial Sense News Release Tobacco smoking rates are decreasing in people with major depression and substance use disorder Upcoming Meetings/Events Meeting/Event NIH Digital Health Interventions Workshop Tuesday, July 12, 2022 to Wednesday, July 13, 2022 | Virtual Meeting/Event Impact of Comorbid COVID-19 and Substance Use During Pregnancy on Fetal and Infant Development Workshop Wednesday, July 20, 2022 10:00am to 5:00pm | Virtual Looking for Treatment? Use the SAMHSA Treatment Locator or call 1-800-662-HELP (4357). Participate in a Clinical Trial Use the NIDA Clinical Trials Locator - answer a few simple questions and get contact information for studies near you.