3D Human Tissue Models for HIV and Related Comorbidities: How Can Organoids and Microphysiological Systems Advance the Field?



Additional Information

The National Institute of Allergy and Infectious Diseases (NIAID) Division of AIDS (DAIDS), in partnership with other NIH Institutes and Centers, is planning a 2-day workshop entitled “3D Human Tissue Models for HIV and Related Comorbidities: How Can Organoids and Microphysiological Systems Advance the Field?” to be held virtually on September 20th and 21st, 2022.

This workshop will bring together experts in the HIV and non-HIV fields involved in research with 3D human tissue models to understand potential synergies of interest to academics, industry, and regulators. Through this workshop, we aim to bridge and understand the concepts, translational potential, and opportunities for 3D tissue models to advance basic and translational research for HIV and related comorbidities, including tuberculosis and substance use and dependence, across the age spectrum. 

Topics to be discussed are expected to include:

  • What is the current state of 3D human tissue model technology?
  • What can 3D models reveal about HIV disease and HIV pathogenesis?
  • What insights can 3D models provide about the biology of HIV-related comorbidities, including coinfections such as tuberculosis, SARS-Cov2, and substance use and dependence?
  • What are potential preclinical and clinical applications of 3D human tissue models for HIV?
  • How might 3D models assist in the development of agents for HIV prevention, treatment, and cure?
  • How could 3D models contribute to HIV drug development for pediatric and maternal populations?
  • How well can 3D tissues model human vaccine responses?
  • What are the analytical and regulatory landscapes for the use and utility of 3D human tissue models?

Tentative Virtual Workshop Schedule:

  • Tuesday, September 20th, 2022: 10:00 AM - 2:45 PM, EDT
  • Wednesday, September 21st, 2022: 10:00 AM - 2:45 PM, EDT

Further information will be forthcoming soon. We hope you’ll be able to join us, please save these dates.

For the Organizing Committee:

  • Melanie Ott, MD, PhD; Gladstone Institutes, University of California San Francisco
  • Lishomwa Ndhlovu, MD, PhD; Weill Cornell Medicine
  • Patricia D’Souza, PhD; NIH/NIAID/DAIDS
  • Passley Hargrove-Grimes, PhD; NIH/NCATS
  • Patrick Jean-Philippe, MD; NIH/NIAID/DAIDS
  • Tania Lombo Rodriguez, PhD; NIH/NIAID/DAIDS
  • Milton Maciel, PharmD, PhD; NIH/NIAID/DAIDS
  • Bob Mahon, PhD; NIH/NIAID/DAIDS
  • Sai Majji, PhD; NIH/NICHD
  • Amy Palin, PhD; NIH/NIAID/DAIDS
  • Betty Poon, PhD; NIH/NIAID/DAIDS
  • Anjali Singh, PhD; NIH/NIAID/DAIDS
  • Hans M. L. Spiegel, MD, DrMedSc; NIH/NIAID/DAIDS
  • Danilo Tagle, MS, PhD; NIH/NCATS
  • Vasundhara Varthakavi, DVM, PhD; NIH/NIDA
  • Jon Warren, PhD; NIH/NIAID/DAIDS
  • David Weinberg, PhD; NIH/NICHD
  • Da-Yu Wu, PhD; NIH/NIDA
  • Dwight Yin, MD, PhD; NIH/NIAID/DAIDS

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