21-002797

Submitted by mahonkg on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Production of custom sgRNA library
Contracting Office
National Institute on Aging (NIA)

Contact Points

Primary Contract Specialist

Malita
Dyson
malita.dyson@nih.gov

Secondary Contracting Officer

Katie
Cartwright
katie.cartwright@nih.gov
NAICS Code Number
541714
Research and Development in Biotechnology (except Nanobiotechnology)
Small Business Size Standard
1000
Estimated Period of Performance
2/29/2021 to 12/31/2021
Delivery of Goods
N/A
Set-Aside Status
Full Set Aside
Set-Aside Type
Small Business (SB)
Competition Status
Non-Competitive
Vendor Name
Cellecta, Inc.
Vendor Address
320 Logue Ave
Mountain View, CA 94043
Single-Sole Source Determination
Guide designs for Cellecta’s libraries incorporate state-of-the-art design criteria to ensure the most effective knockout possible. In addition, the region of the sgRNA interacting with the Cas9 nuclease has been optimized for higher efficiency knockout by incorporating the “HEAT” design. Cellecta has shown that specific modifications to the Cas9-binding region of sgRNA significantly improve the effectiveness of gene knockout and that CRISPR libraries containing constructs with these modified sgRNA sequences generate stronger and more robust results than those with the standard sgRNA.

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.