21-004093

Submitted by mahonkg on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
OKO stage top incubator
Contracting Office
National Institute on Aging (NIA)

Contact Points

Primary Contract Specialist

Randall
Carter
randall.carter@nih.gov
NAICS Code Number
333314
Optical Instrument and Lens Manufacturing
Small Business Size Standard
500
FPDS Classification Code
6515
Delivery of Goods
60-90 Days ARO
Set-Aside Status
Not Set Aside
Competition Status
Competitive
Vendor Name
NIKON INSTRUMENTS INC.
Vendor Address
1300 WALT WHITMAN RD FL 2
MELVILLE, NY 11747
Congressional District: NY - 3
Single-Sole Source Determination
This acquisition is restricted to Nikon Instruments, Inc. because Nikon Instruments, Inc. is the only supplier capable of providing a stage top chamber for an existing microscope for integration with the pre-existing Nikon Instruments for iPSC Neurodegenerative Diseases Initiative (INDI) Project within the new Center for Alzheimer’s Disease and Related Dementias.
Background/Description of Requirement

Acquisition Purpose and Objectives:

This acquisition is necessary to provide a stage top chamber for an existing microscope to the iPSC Neurodegenerative Diseases Initiative (INDI) Project within the new Center for Alzheimer’s Disease and Related Dementias.

Description of the Item or Service:

Stage Top microscope Chamber is to provide a stable environment for iPS cells to survive during long acquisition times on the microscope.  The cells need certain temperature, humidity and CO2 level in order to survive.  If they do not have the support of the chamber, the cells will not survive which will render the data collection invalid.

Salient Characteristics:

a.  Temperature Range: from 3°C above ambient to 60°C
b.  Temperature Accuracy: ± 0.1°C in sample feedback mode, ± 0.3°C in chamber    feedback mode
c.  Compatible with: Bold Line T, UNO Combined and H401-T Controllers
d.  Chambers available for any XY stage / piezo insert
e.  Embedded temperature sensor in heated glass lid and in chamber body
f.  Interchangeable magnetic inserts allow to host Petri, Slides and MW Plates
g.  Magnetic locks hold the Petri, the Slides and the MW Plates in the correct position inside the chamber
h.  Perfusion holes available for inlet and outlet of tubes
i.  Sliding lid allows easy access to the sample
j.  Optional lids are available for Koehler Illumination, laser safety and injection during imaging

Manufacturer warranty for one calendar year beginning date of receipt.

Quantity:

1 (One) - Stage Top Chamber

Project Background: 

The NIA Center for Alzheimer's Disease and Related Dementias (card) is working to create a national resource of isogenic sets of Alzheimer’s Disease and Related Dementias mutated iPSC lines, complimented by foundational phenotypic data sets from differentiated disease-relevant cells derived from these lines. We are working to create a national resource of isogenic sets of Alzheimer’s Disease and Related Dementias mutated iPSC lines, complimented by foundational phenotypic data sets from differentiated disease-relevant cells derived from these lines. This stage top chamber furthers the functionality of the Biopipeline microscope, allows for long term cell imaging while maintaining environmental stability.  This is essential in keeping the cells alive especially when doing extended acquisitions with this microscope. The iPS cell lines are essential in studying the pathogenesis of neurodegenerative these diseases.

 

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.