Submitted by fratecm on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
ATAC-Seq Kit, 16 rxns
Contracting Office
National Institute of Mental Health (NIMH)

Contact Points

Primary Contract Specialist


Secondary Contracting Officer

NAICS Code Number
Research And Development In The Physical, Engineering, And Life Sciences (Except Nanotechnology And Biotechnology)
Small Business Size Standard
FPDS Classification Code
Delivery of Goods
7 days ARO
Competition Status
Brand Name Only
Vendor Name
Active Motif, Inc.
1914 Palomar Oaks Way
STE 150
Carlsbad, California
Single-Sole Source Determination
The National Institute of Mental Health, Section on Developmental Neurogenomics, requests to generate assays of ATAC-Seq using the ATAC-Seq kits from Active Motif. The assay of the transposase-accessible chromatin with sequencing (ATAC-Seq) is a popular method for determining chromatin accessibility across the genome. By sequencing regions of open chromatin, ATAC-Seq can help us uncover how chromatin packaging and other factors affect gene expression. To complete this objective and to further increase our sample size, we must ensure that our ATAC-Seq kits are purchased from the same manufacturer for continuity of our current study. The continuity is absolutely essential for the validity of our work and has to be in place for us to address the key scientific questions for this project. Using a different vendor would cause irreparable harm to our ongoing experiments and research. In conclusion, we require the same vendor and assays in order to compare the data that has been previously collected thus far in our earlier assays from Active Motif.
Background/Description of Requirement

The Human Genetics Branch, Section on Developmental Neurogenomics conducts a series of studies that aim to better understand the neurobiology of sex Chromosome Aneuploidies as important yet understudied neurogenetic disorders in their own right and provides insight into the biology of sex-difference, genetic regulation of brain organization, and mechanisms of genetic risk of common psychiatric syndromes. Over the past two years, we have performed the assays of ATAC-Seq using the ATAC-Seq kits and are currently in need to purchase an additional 12 ATAC-Seq kits for assays. This is considered a follow-on acquisition to POTS #23-002783/PO# 7054439 from February 17, 2023.

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.