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Software for data acquisition, processing, and analysis of human photosensitivity data
The software component for the Ocular Photosensitivity Analyzer is a sophisticated, multilingual platform tailored to support comprehensive photosensitivity. With a user-friendly interface, it supports eight languages—French, English, German, Italian, Spanish, Portuguese, Arabic, and Hebrew—ensuring broad accessibility. The software performs real-time data acquisition, processing, and analysis, employing advanced algorithms to provide accurate results. It offers precise control over LED stimuli parameters, enabling customizable test protocols. Patient management is streamlined with a comprehensive system for storing and tracking demographic information, test results, and historical data. The software integrates real-time environmental monitoring, recording conditions such as temperature and humidity to ensure accurate analysis. Robust data storage solutions, including automated backups to the USB external hard-drive, guarantee data integrity and security. Additionally, built-in compliance with regulatory standards ensure that all studies meet necessary guidelines, making the software both reliable and efficient for advanced research applications. This agreement also covers the effort of biomedical engineers Cor Rowaan and Alex Gonzalez to provide instructions for the assembly process, device configuration and training to be held over two days via zoom, and an in-person option is available.
The influence on light on mood disorders has been well established. Seasonal and time of day fluctuations are associated with both acute mood changes as well as patterns of incidence of depressive episodes. Bipolar disorder (BPD) has been shown to have increased reactivity to light at both the individual and aggregate levels. Our recent finding that environmental light at night was associated with bipolar disorder and sleep disturbances in a large general population study of US adolescents provided evidence that light sensitivity may emerge as early as the teen years. (Paksarian, 2020). For example, recent studies that have shown that higher nighttime illuminance is associated manic/hypomanic symptoms (Esaki, 2020).
Through a collaborative effort between the National Institute of Mental Health Intramural Research Program, the Oregon Health Sciences Institute, and the Bascom Palmer Institute in the Department of Ophthalmology at the University of Miami, we will systematically examine photosensitivity in people with BPD, MDD and controls in the NIMH Intramural Program Rhythms and Blues Research Protocol. We will examine both males and females across the age spectrum to test whether there are gender and developmental differences in photosensitivity. Correlates of photosensitive will include patterns of DMLO on prior night, olfactory sensitivity, heart rate reactivity, mood states and sleep. The study will also examine the stability of phonocentricity at two week and three-month intervals.
The objective of this agreement is to: (1) purchase the software for downloading, processing and analysis of the photosensitivity data from this study; and (2) provide levels of effort of personnel for training, consultation on administration of the experiment, and interpretation of the findings from the study. The University of Miami personnel will provide software for extracting, processing, and analyzing the data, and allocate personnel time for the oversight of study progress, and training of NIMH personnel in the setup, performing the experiment, and ensure comparability with previous studies of this equipment to measure photosensitivity in people with Traumatic Brain Injury at the Oregon Health Sciences University. Comparability with basic science studies of photosensitivity will be informed by basic science studies in Oregon and the NIMH Laboratory by Collaborators Matthew Butler, PhD and Samer Hattar, Ph.D. We will work with the personnel from the University of Miami and collaborators from the Oregon Health Sciences University to standardize the procedure, data processing and analysis of the data for the study.
Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.
All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.
All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.