Submitted by whipple on Tue, 06/14/2022 - 10:43
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Annual software license for PerkinElmer Signals Image Artist software
Contracting Office
National Center for Advancing Translational Sciences (NCATS)

Contact Points

Primary Contract Specialist

NAICS Code Number
Small Business Size Standard
FPDS Classification Code
Estimated Period of Performance
07/01/2022 - 06/30/2023
Delivery of Goods
30 days after receipt of order
Set-Aside Status
Not Set Aside
Competition Status
Brand Name Only
Vendor Name
PerkinElmer Informatics, Inc.
940 Winter Street
Waltham, MA 02451
Single-Sole Source Determination
NCATS ITRB has been effectively using the PerkinElmer Columbus software system for integration of critical scientific systems and applications, and the PerkinElmer Signals Image Artist™ software system is designed as an extension of Columbus. Extending the current configuration of VMware will allow our infrastructure to operate in an optimal state in terms of cost, high availability and robustness. Based on our current deployment of this software family, we have identified areas of optimization and improvement and the vendor has customized the software accordingly. Changing integration software would not only have a substantial financial cost (software, customization and staff labor) but the possible down time while changing systems over could leave NCATS open to a critical failure which could result in additional time and money repairing equipment and installing additional patches, etc. Signals Image Artist™ software is the only commercial product that will provide this consistency of analysis. This software is not sold by vendors other than PerkinElmer.
Background/Description of Requirement
  1. Statement of Need and Purpose:The purpose of this procurement is to acquire an Annual Software license for PerkinElmer’s Signals Image Artist software.
  2. Background Information and Objective:The NCATS Chemical Genomics Center (NCGC) is tasked with identifying and developing novel small molecule leads against a wide spectrum of human disease targets, which it accomplishes by screening thousands of small molecules in collaboration with both intra-and extramural researchers. In pursuit of this goal, the Center has a strong internal transdisciplinary team of scientists who continually discover novel small molecules for application against a wide range of human diseases.

NCATS needs to upgrade to the PerkinElmer Signals Image Artist™ database and analysis software system to utilize newly released features. These new features include advanced network/data security, the ability to batch-process large numbers of fluorescence microscopy images via modern high-performance computing clusters, and improved algorithms for segmentation and analysis of cell morphology from fluorescence microscopy digital image sets. For 10+ years, NCATS has used the PerkinElmer Columbus database and analysis software system for management and analysis of digital microscopy images. However, the Columbus software will no longer be supported/upgraded in the future by PerkinElmer. In addition to the new essential features in Signals Image Artist™, this new software system will also continue to provide the legacy analysis functions that were previously provided by the Columbus software. Many ongoing research projects that have been analyzed with Columbus software at NCATS require consistent image analysis over time. This upgrade to Signals Image Artist™ software is the only commercial product that will provide this consistency of analysis. This software is not sold or supported by vendors other than PerkinElmer.

  1. Specific Requirements: The vendor will supply support and licenses as shown below:

PART #                               DESCRIPTION                                               QTY

INF02358                          Signals Image Artist™ software                5

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.