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The significant, essential physical, functional, performance, or material element(s) that are the Government’s minimum acceptable standards for an equivalent system to meet the government’s objective are as follows:
An equivalent microscope camera shall have:
• Extreme Speed: 498 frames per second (fps) at 8-bit readout mode, facilitating rapid data acquisition for dynamic imaging studies.
• Large Field of View: 29.4 mm diagonal field of view, maximizing data capture in a single frame, crucial for efficiency in image acquisition.
• High Sensitivity: Near-perfect 96% quantum efficiency and low 0.7 e- read noise ensure clear imaging, even in low-light conditions.
• High Resolution: 6.5 ìm x 6.5 ìm pixels provide detailed images suitable for live cell imaging at 40x and 60x magnification.
• Superior Background Quality: Pattern Noise Reduction Technology and Correlated Noise Reduction Technology guarantee clean, pattern-free images.
• Integration set-up with Existing Equipment: Seamless attachment to the laboratory's Nikon spinning disk microscope for enhanced imaging capabilities.
The microscope camera shall be warranted, and the Contractor shall warrant its equipment against defects in material, fabrication, or workmanship for a minimum of one (1) year from the date the Government accepts delivery of the item.
The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease for all people.
The intramural laboratory within the NINDS Neurogenetics Branch’s IND Section focuses on research efforts for identifying intersecting mechanisms of neurodegenerative diseases, with an ultimate goal of developing targeted, disease-modifying therapies for affected patients.
Imaging capabilities is critical for studying human stem cell-derived neurons in the context of neurodegenerative diseases. Therefore, NINDS has identified a need for a microscope camera in order to accelerate its research progress, enhance data quality, and gain deeper insights into complex mechanisms underlying neurodegenerative diseases, ultimately contributing to advancements in biomedical science.
The brand-name item that meets the need of this procurement is Nikon Instruments, Inc.’s Kinetix back-illuminated sCMOS (Part #77018310), which relies on imaging capabilities to study human stem cell-derived neurons.
Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.
All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.
All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.