Contact Points
Trade Name: Manipulator Control System
Brand name/description: Control Cubes, PatchPad Controller and Scientifica Control Racks
Salient characteristics: The significant, essential physical, functional, performance, or material element(s) that are the Government’s minimum acceptable standards for an equivalent system to meet the government’s objective are as follows:
• a quantity of two (2) manipulator control boxes that can hold a micro electrode for single-cell or axonal recordings on brain slices
• a quantity of two (2) control cubes through the control of manipulator control boxes that have the functionality to move the manipulators with electrodes through 3-D dimensional spaces to aim for a cell
• a quantity of one (1) patch pad controller that has the functionality to move the microscope lens to locate and visualize the cells
• Software to support its system
The manipulator system shall be warranted, and the Contractor shall warrant its equipment against defects in material, fabrication, or workmanship for a minimum of one (1) year from the date of installation, inspection by the Government, and acceptance. Warranty shall not include routine or periodic maintenance services.
PURCHASE DESCRIPTION
Statement of Need and Purpose: The purpose of this requirement for the National Institute of Neurological Disorders and Stroke (NINDS), Laboratory of Circuits, Synapses, and Molecular Signaling (LCSMS) is to acquire Scientifica LLC Manipulator Control System Control Cubes, PatchPad Controller and Control Racks or equal to conduct physiological experiments from both mice and nonhuman primates. Single cell responses can be recorded from a glass electrode held by the manipulators of the system.
Background Information and Objective:The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease for all people. The NINDS Laboratory of Circuits, Synapses, and Molecular Signaling (LCSMS) studies fundamental issues of synaptic transmission, neuronal excitability, neuromodulation, and neural circuit activity using animal models (mouse and monkey). These issues are related to human neurological disorders, such as Alzheimer’s and other neurodegenerative disorders, and are explored in brain areas including (but not limited to) the amygdala, basal forebrain cholinergic areas, the ventral hippocampus, and the prefrontal cortex.
A major line of research employs patch-clamp recording systems to interrogate cellular properties in the brain. Therefore, NINDS has identified a need for Scientifica LLC brand-name patch-clamp recording manipulator system to further its ongoing research, in which single cell responses can be recorded from a glass electrode held by the manipulators of the system. This will enable the laboratory to continue accelerating its critical research studies related to human neurological disorders for enhancing data quality and gain deeper insights into complex mechanisms underlying neurodegenerative diseases such as Alzheimer’s, ultimately contributing to advancements in biomedical science.
The brand-name item that meets the need of this procurement is Scientifica LLC Manipulator Control System Control Cubes, PatchPad Controller and Control Racks, in which single cell responses can be recorded from a glass electrode held by the manipulators of the system.
Generic Name of Product: Manipulator control boxes, control cubes and controller
Manufacturer: Scientifica LLC
Trade Name: Manipulator Control System
Brand name/description: Control Cubes, PatchPad Controller and Scientifica Control Racks
Salient characteristics: The significant, essential physical, functional, performance, or material element(s) that are the Government’s minimum acceptable standards for an equivalent system to meet the government’s objective are as follows:
a quantity of two (2) manipulator control boxes that can hold a micro electrode for single-cell or axonal recordings on brain slices
a quantity of two (2) control cubes through the control of manipulator control boxes that have the functionality to move the manipulators with electrodes through 3-D dimensional spaces to aim for a cell
a quantity of one (1) patch pad controller that has the functionality to move the microscope lens to locate and visualize the cells
Software to support its system
The manipulator system shall be warranted, and the Contractor shall warrant its equipment against defects in material, fabrication, or workmanship for a minimum of one (1) year from the date of installation, inspection by the Government, and acceptance. Warranty shall not include routine or periodic maintenance services.
Quantity:
Manipulator control boxes: Two (2)
Control cubes: Two (2)
PatchPad controller: One (1)
Delivery Date: The Contractor shall deliver the equipment described above within 90 days after receipt of order (ARO). The equipment shall be delivered to the NINDS delivery address under Purchase Description 8. below between the hours of 8:00 am and 5:00 pm, Eastern Daylight Time, Monday through Friday (except federal holidays). Delivery shall be Freight on Board (FOB) destination and shall include inside delivery. Details of delivery, installation, and onsite support shall be coordinated with the Contracting Officer’s Representative (COR).
Delivery Address:
NINDS/LCSMS
Bldg. 35 / Rm 3B-1010
35 Convent Drive
Bethesda, MD 20892
Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.
All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.
All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.