NIH-NINDS - 22-009294 - Notice of Intent

Submitted by patelsnv on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Genotyping Mouse Lines
Contracting Office
National Institute of Neurological Disorders and Stroke (NINDS)

Contact Points

Primary Contract Specialist

Valerie
Gregorio
valerie.gregorio@nih.gov
NAICS Code Number
334516
Analytical Laboratory Instrument Manufacturing
Small Business Size Standard
1,000 employees
FPDS Classification Code
N/A
Estimated Period of Performance
N/A
Delivery of Goods
BLDG 35 RM 3C1002
Set-Aside Status
Not Set Aside
Competition Status
Brand Name Only
Vendor Name
Transnetyx
Address
8110 Cordova Rd, Suite 119
Cordova, TN 38016
United States
Single-Sole Source Determination
We are requesting a service to be rendered by the company Transnetyx. Transnetyx is the world leader in
commercial offering of genotyping services. I am not aware of another company that offers such service at the
convenience and cost of Transnetyx. In addition, the Cellular Neurophysiology Section has been using this
company for many years. We have used Transnetyx to genotype many custom and non-standard mouse lines and
have established that the genotyping for these mouse lines is reliable. If we use another company, the genotyping
for our non-standard mouse lines will need to be reestablished which would take a substantial amount of time and
would be inefficient.
Background/Description of Requirement

Research in the Cellular Neurophysiology Section focuses on circuit and cellular properties of dopaminergic neurons located in the midbrain. We are interested in the physiology of a subset of dopamine neuron located in the substantia nigra pars compacta (SNc) that undergo selective cell death in Parkinson’s patients.  Specifically, we are interested in understanding how synaptic and intrinsic conductances differ among subpopulations dopamine neurons with the hope that this may provide insight to why SNc dopamine neurons are particularly vulnerable in Parkinson’s disease.  Our goal is to identify novel physiological and genetic markers in single SNc dopamine neurons which may be useful in defining subpopulations of these neurons in a meaningful way. 

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.