NIH-NINDS - 22-011579 - Notice of Intent

Submitted by patelsnv on Mon, 07/25/2022 - 11:58
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
EPC 10 USB Patch Clamp Amplifier
Contracting Office
National Institute of Neurological Disorders and Stroke (NINDS)

Contact Points

Primary Contract Specialist

NAICS Code Number
Analytical Laboratory Instrument Manufacturing
Small Business Size Standard
1,000 employees
FPDS Classification Code
Estimated Period of Performance
Delivery of Goods
BLDG 35 RM 2B1015
Set-Aside Status
Not Set Aside
Competition Status
Brand Name Only
Vendor Name
Havard Apparatus
84 October Hill Rd., Suite 10
Holliston, MA 10746-1388
United States
Single-Sole Source Determination
EPC-10 Patch Clamp Amplifier is sole amplifier to provide the function of the membrane capacitance measurement in studying vesicle transmission. Currently, we have 6 EPC-10 Patch Clamp Amplifiers in our lab. So, we will order a new EPC-10 amplifier from the same company, Harvard Apparatus. It will make our use and maintenance more convenient.
Background/Description of Requirement

The National Institutes of Health (NIH) is the nation’s leading medical research agency and the primary Federal agency conducting and supporting medical discoveries that improve people’s health and save lives. The National Institute of Neurological Disorders and Stroke (NINDS) mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease.

 An EPC-10 amplifier, a basic electrophysiological experiment, has been used to catch the tiny electronic signals induced by vesicle transmission. We will combine the new EPC-10 amplifier with a new imaging system to study the vesicle transmission at a single vesicle level, which will significantly benefit our studies.

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM)

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.