NINDS 25-002403

Submitted by patelsnv on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Mouse Feed with L-Lysine (13C, 99%)
Contracting Office
National Institute of Neurological Disorders and Stroke (NINDS)

Contact Points

Primary Contract Specialist

ELAINE
ESTRELLA
elaine.estrella@nih.gov
NAICS Code Number
325414
Biological Product (except Diagnostic) Manufacturing
Small Business Size Standard
OTSB
FPDS Classification Code
6810
Estimated Period of Performance
6 MONTHS TO 1 YEAR
Delivery of Goods
NINDS BLDG 35 RM 2A-211
Set-Aside Status
Not Set Aside
Competition Status
Brand Name or Equal
Brand Name
CAMBRIDGE ISOTOPE LABORATORY
Rationale/ Salient Characteristics
Mouse Feed meeting all nutritional requirements for mice, compressed into standard pellet format, all L-Lysine in feed containing 13C at 99% incorporation.
Single-Sole Source Determination
Market research conducted by the CO shows that this is the only company that can provide the necessary mouse feed that meets salient characteristics that meets government requirement.
Background/Description of Requirement

Parkin is the leading autosomal recessive cause of Parkinson’s disease. We identified that Parkin is part of a pathway that turns over mitochondrial protein through a process known as mitophagy. However, the extent to which this pathway is responsible for mitochondrial protein turnover in vivo is not known. The procurement of the mouse feed will allow for metabolic labelling of mice so that mitochondrial protein turnover can be  measured by LC-MS/MS based proteomics.

 

The request is for (1) Mouse Express L-Lysine (13C, 99%) Mouse Feed that must be deliverd within 6-8 weeks after production. 

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.