POTS23-007118

Submitted by fratecm on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Single cell RNA sequencing transcriptome
Contracting Office
National Institute of Mental Health (NIMH)

Contact Points

Primary Contract Specialist

Tam
Ngo
ngot@mail.nih.gov
NAICS Code Number
541714
We are studying the changes of gene expression from neuropsychiatry animal models. To read RNA expression from different types of cortical neurons, we use single cell RNA transcriptome kits from 10x Genomics.
Small Business Size Standard
Not Small Business
Delivery of Goods
09/26/2023
Set-Aside Status
Not Set Aside
Competition Status
Brand Name or Equal
Rationale/ Salient Characteristics
The Chromium Next GEM Single Cell 3’ Reagent Kits enables deep profiling of complex cell populations with high-throughput 3’ digital gene expression and feature analysis of individual cells. Single-cell sequencing provides a number of advantages, including:
• Single-cell sequencing can detect biologically relevant gene expression signals masked by bulk measurement for a wide dynamic range of individual cells per chip across heterogeneous cell types (up to 8,000 cells per LT chip, up to 80,000 cells per standard throughput chip, up to 320,000 cells per HT chip)
• Rare or novel cell types may also be uncovered and characterized based on environmental or experimental conditions.
• Simultaneous assessment of many phenotypes (e.g. gene expression and protein abundance)
• Targeted gene expression analysis with pre-designed and custom gene panels

Additionally, there are Chromium Next GEM Automated Single Cell 3’ Reagents to be run on the Chromium Connect.
Single-Sole Source Determination
Chromium Nex GEM single cell kits listed herein is available from only one source, and competition is precluded for the reasons indicated below. There are no substitutes available.

This acquisition is restricted to 10x Genomics, Inc.
10x Genomics.Inc.
6230 Stoneridge Mall Road
Pleasanton, California, 94588-3260
Background/Description of Requirement

3 kits:

  • One (1) x Chromium Next GEM Single Cell 3' Kit v3.1, 4 rxns
  • One (1) x Chromium Next GEM Chip G Single Cell Kit, 48 rxns
  • One (1) x Chromium Next GEM Single Cell 3' Kit v3.1, 4 rxns

Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.