POTS24-006267

Submitted by fratecm on
Post Date/ Solicitation Issue Date
Closing Response Date
Proposed Award Date
Project Title
Inscopix nVue 2.0 System and maintenance agreement
Contracting Office
National Institute of Mental Health (NIMH)

Contact Points

Primary Contract Specialist

Tam
Ngo
ngot@nih.gov
nVue System for Dual Color In Vivo Imaging Dual color imaging platform for visualization of large-scale neural circuit dynamics in freely behaving rodents. Includes miniature microscope, data acquisition box, and Inscopix Data Acquisition software.

Salient characteristics:

- Equipped with 2 LEDs but set to different wavelengths (one blue LED and one lime LED).
- Hardware is able to multiplex through both LEDs to allow simultaneous imaging of two dynamic populations of neurons, neurotransmitters, or blood cells/vessels
- Must will come with upgraded large-scale dual color calcium imaging in freely behaving rodents.
- Must come with miniature microscope.
- Must have DAQ box which allows for seamless communication with an external hardware device and coordinates or controls multiple devices during an experiment.
- Must have Inscopix Data Acquisition Software (software includes device control for two imaging LEDs in dual dynamic, dynamic-static, neurotransmitter, and blood flow imaging modes)
- Must be compatible and integratable with large data sets, accessories, and other hardware acquired with nVue system
- As part of purchase OEM must provide free repairs/or replacement for any hardware damage no matter the cause (user , animal, unknown)
- Must come with online access to user manuals, training, protocols and training videos
- Must come with online support for experimental design.
Small Business Size Standard
Small Business
FPDS Classification Code
31005
Estimated Period of Performance
09/01/24 -08/30/25
Delivery of Goods
30 days from date of order
Set-Aside Status
Not Set Aside
Set-Aside Type
Small Business (SB)
Single-Sole Source Determination
Brand-name or Items peculiar to one manufacturer.
The nVue 2.0 System and maintenance agreement from Inscopix listed herein is available from only one source, and competition is precluded for the reasons indicated below. There are no substitutes available.

This acquisition is restricted to INSCOPIX, INC., 2462 Embarcadero WayPalo Alto, CA 94303 USA Tel: (650) 600-3886 Email: sales@inscopix.com Web: www.inscopix.com. Robby Padia at rpadia@inscopix.com

Background/Description of Requirement

Current approaches to investigations of brain circuits and systems require detailed analyses of neuronal circuit dynamics at cellular or greater resolution across multiple brain regions. The nVue 2.0 Dual Color Miniscope Imaging system allows the simultaneous detection the of two independent fluorophores. The nVue 2.0 system provides an innovative solution for the investigation of inter-regional functional connectivity, functional cell type mapping and microcircuit functioning, all in the brain of freely behaving animals.  The unique system will greatly enhance the NIMH mission statement. Additionally, this system is solely obtainable via Inscopix. Due to the importance of this system the UNAM needs a dedicated system within their own lab to continue their research unabated.  The system must match existing system due to data sets already obtained and for continuity and reproducibility of existing and future experiments.

The essential characteristics of the nVue 2.0 System from Inscopix that limit the availability to a sole source are this is the only commercially available thru upgrade to the fully integrated implantable microscope into small rodent’s brain with combined optogenetics capabilities usable in free ranging test animals with complete hardware and software components. Only this suggested source can furnish the upgrades and requirements, to the exclusion of other sources, because as market research has shown Inscopix is the only commercially available system.  Additionally, Inscopix products have been awarded based on Sole Source Justification in previous attached awards to Dr. Penzo.  The upgrades meet all the technical requirements as listed in the product description salient requirements as reproduced below.

 

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Interested parties may identify in writing their interest and capability in response to this requirement. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.

All responses must be received by closing date and must reference the announcement. Responses may be submitted electronically to the attention of the contract specialist. Fax responses will not be accepted.

All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.