Methamphetamine overdose deaths rise sharply nationwide
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NIH-supported study finds biggest increase among American Indians and Alaska Natives
Latest from NIDA
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Combination medication may be effective in treating adults with methamphetamine use disorder
ADAPT-2 Trial Results Deliver a Breakthrough in Long Search for Methamphetamine Use Disorder Medication
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A combination of bupropion and naltrexone successfully reduced methamphetamine use
People With SUDs Have Increased Risk for COVID-19 and Worse Outcomes
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People with a substance use disorder (SUD) at any time in their lives are 1.5 times more likely to contract COVID-19 than those without an SUD, and those with a...
Physician-pharmacist collaboration may increase adherence to opioid addiction treatment
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NIH-supported pilot study found team-based approach may improve buprenorphine care
Substance Use Status Important When Developing HIV Therapies
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Animal studies suggest that subjects with HIV who suffer from opioid use disorders may have higher viral reservoirs in the central nervous system than non-opioid users.
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Patients in treatment for opioid use disorder (OUD) who were more comfortable making decisions when they did not know the probability of outcome had a higher risk of using opioids...
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Annual Monitoring the Future (MTF) survey results released.
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NIDA-funded research aims to help understand teen drug use and its effects
Unraveling neuroHIV in the Presence of Substance Use Disorders
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These reviews address how each of these addictive substances and HIV individually or collectively affect the immune system and subsequent clinical and behavioral outcomes
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A specific collection of neurons in the basolateral amygdala, a brain region crucial for affect, was active when mice experienced pain. Deactivating this collection of neurons resulted in a loss...
Elite Controllers May Hold Key to an HIV Cure
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"Science" Magazine Breakthrough of the Year Runner Up for 2020
On World AIDS Day, Celebrating Scientific Advances and Confronting the Complexities of HIV and Substance Use
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We applaud the substantial strides made, while recognizing the challenges that need to be addressed.
Amy Hauck Newman appointed to lead NIDA’s Intramural Research Program
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Dr. Newman officially began her new position at the NIDA IRP on November 22, 2020.
HIV and Methamphetamine Use: Double Jeopardy for Transmission of the Novel Coronavirus.
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The authors suggest that co-occurring methamphetamine use and HIV present a double jeopardy for COVID.
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There is an alarming increase in deaths involving the stimulant drugs methamphetamine and cocaine.
Neighborhood conditions associated with children’s cognitive function
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NIH-funded research from ABCD Study finds association despite household income.
NIH study tests a comprehensive model intervention to reduce opioid overdose deaths in hard-hit communities
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COVID-19 brings challenges, learning opportunities
NIH-funded study links adolescent brain differences to increased waist circumference
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Finding from ABCD Study elucidates neural mechanisms that may underlie early weight gain
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People with SUDs may be particularly vulnerable to COVID-19 and its most adverse health outcomes
Narrative of Discovery: The Quest for a Medication to Treat Methamphetamine Addiction, Part 5
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In the summer of 2019, Dr. Linda Dwoskin and her research team felt they were in a promising place in their decades-long search for a treatment for the 700,000 Americans...
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Increases are among the largest in history of national study
Gaps in Substance Use Treatment Services for HIV Patients Around the Globe
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Substance use is common among people living with HIV and is associated with less successful HIV treatment outcomes. Integrating substance use services into HIV care is a promising strategy to...
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Significant increases in many kinds of drug use have been recorded since March
Substance use disorders linked to COVID-19 susceptibility
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NIH research finds higher risk and worse outcomes for those with addiction
Cocaine Triggers Endocannabinoid Release Through a Novel Mechanism
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Cocaine can trigger release of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the ventral tegmental area of the midbrain in mice, and this may play a role in cocaine use disorder.
Prenatal Cannabis Exposure Alters Brain Reward Circuitry in Male Rats
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Prenatal cannabis exposure (PCE) increased sensitivity to THC in male rats, but not female rats, during pre-adolescence. PCE increased dopamine release in response to THC and altered the properties of...
Research at the Intersection of HIV with Substance Use Disorders amidst the COVID-19 Pandemic
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We are prioritizing research into how the coexisting crises of COVID-19, HIV, and substance use, including the opioid crisis, combine to create a disastrous storm, taking lives and overtaxing America’s...
Two Different Brain Regions Are Linked With Nicotine Addiction Severity and Nicotine Withdrawal
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Activity in the striatum of people who smoke changed less in response to positive feedback/reward than in nonsmokers; this effect was more pronounced with greater addiction severity. Activity of the...
Treating Substance Use Disorders Can Reduce HIV Burden in U.S. Cities
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Concerted efforts and substantial investments in HIV prevention and care in the United States have resulted in considerable reduction in new diagnoses and death since the mid-1990s. To identify best...