People with substance use disorders may be at higher risk for SARS-CoV-2 breakthrough infections
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Co-occurring health disorders appear to contribute to increased risk, NIH study suggests
Latest from NIDA
NIDA’s HIV Research Program: A Longstanding Institute Priority Continues Under a New Name
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To help combat the stigma that still attaches to HIV, we decided to rename our program the HIV Research Program.
Developmental Nicotine Exposure in Mice Affects Epigenetic Factors in the Brain Across Multiple Generations
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Epigenetic changes that can persist for generations after nicotine exposure may predispose children and grandchildren of people who smoke to develop neurological and behavioral disorders.
Methamphetamine-involved overdose deaths nearly tripled between 2015 to 2019, NIH study finds
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Patterns of methamphetamine use have become riskier, diversified across U.S. population
CDC Health Advisory: Increases in Availability of Cannabis Products Containing Delta-8 THC and Reported Cases of Adverse Events
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CDC Alert on the Increased availability of cannabis products containing delta-8 tetrahydrocannabinol (THC) and the potential for adverse events
The ABCD Study Uncovers Relationships Between Socioeconomic Factors, Cognitive Abilities, and Brain Development
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Children with greater access to resources, better social support, and better perinatal health had larger brain surface areas and higher cognitive scores, regardless of family income.
Disparities in opioid overdose deaths continue to worsen for Black people, study suggests
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NIH-supported study underscores the need for racially inclusive approach to address the opioid crisis in hard-hit areas
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Annual NIH-supported study reports changing substance use trends among college students and college-aged adults
Drug overdose deaths in 2020 were horrifying. Radical change is needed to address the drug crisis.
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More people died of overdoses in the U.S. in 2020 than in any other one-year period. These data are shouting for change.
NIH HEAL Initiative: Research Meets the Moment to Address the Opioid Public Health Crisis
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Directors highlight research results from NIH-funded science and community partnerships
Chronic Cocaine Use Changes Brain Structure and Cognitive Function in Rhesus Monkeys
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Specific cocaine-induced decreases in gray matter density were associated with reduced performance on tests of memory and cognition.
NIH-funded study finds overall rate of drug use among 10-14 year-olds remained stable during the 2020 COVID-19 pandemic
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Adolescents experiencing stress, mental health issues, and hardship most likely to use substances
Reduced Activity in One Brain Region Links Childhood Adversity to Aggression/Delinquency and Substance Use in Adolescence
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People who experienced more childhood adversity had higher rates of substance use in late adolescence.
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Punitive policies around drugs contribute to the overwhelming stigma against people with addiction
The Federal Responses to the Drug Overdose Epidemic
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The twin addiction and overdose crises have collided with the COVID-19 pandemic, each exacerbating the deleterious effects of the other
More than 1.5 million children lost a primary or secondary caregiver due to the COVID-19 pandemic
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Addressing the impact of caregiver deaths critical for pediatric mental health, authors note
Preventive Interventions Delivered in Childhood May Reduce Substance Use Over Two Generations
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Children of intervention recipients showed improved developmental functioning before age 5, as well as fewer problem behaviors; better academic, cognitive, and emotional skills; and less risk behavior from ages 6...
Words matter: language can reduce mental health and addiction stigma, NIH leaders say
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Appropriate terminology can improve how people with these conditions are treated in health care settings and society
Emergency department-administered, high-dose buprenorphine may enhance opioid use disorder treatment outcomes
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Study finds treatment is safe and well tolerated in people with opioid use disorder experiencing withdrawal symptoms
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Marijuana use and drinking did not significantly change during the COVID-19 pandemic
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NIH study suggests a link between cannabis use and higher levels of suicidal ideation, plan, and attempt
Using Alcohol and Marijuana Together Exacerbates Negative Consequences in Young Adults
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Simultaneous alcohol and marijuana use is associated with both increased alcohol consumption and greater negative consequences.
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Substance use disorders can increase the risk for becoming severely ill from COVID-19, making vaccinations vital.
Economic Modeling Shows Optimal HIV-Reduction Interventions Depend on the Location
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Researchers identified optimal intervention combinations for six cities (one-quarter of all people with HIV in the U.S.).
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Trial underway to determine whether mobile clinics can help improve health outcomes for people with opioid use disorder
Medication Treatment of Opioid Use Disorder Can Protect Against Overdose Death
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Fewer overdose deaths occurred among adults treated with opioid agonist medications than among those not treated with medication.
Long-lasting medications may improve treatment satisfaction in people with opioid use disorder
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NIH leaders emphasize the importance of patient voices in addiction medication development
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New guidance for researchers establishes a standard THC unit of 5 milligrams.
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A public health approach to drug addiction is critical for population well-being and health equity
Medical records analysis links cannabis use disorder in pregnancy to infant health problems
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Study adds to a growing body of evidence that prenatal exposure to cannabis may be associated with poor birth outcomes