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Government surveys showed that in 2017, an estimated three million people tried marijuana for the first time, just over a million tried cocaine, close to 800,000 tried LSD, and close...
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A study conducted among 517 youth in the rural areas of the southeastern United States demonstrates the effectiveness of a parenting enhancement program in both preventing drug use and obesity...
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Effectively delivering OUD treatment in the justice system will give individuals with OUD a chance of recovery, and will make a huge difference in reducing the toll of the opioid...
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Scientists from NIDA’s Intramural Research Program show that neural mechanisms that control appetitive aggressive behavior are similar to those that control drug-taking and seeking (relapse), suggesting common neurobiological mechanisms of...
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Diversity and inclusion are paramount in all sectors of society, especially in the sciences. Yet it is a well-known (and frequently lamented) fact that males continue to dominate the speaker...
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Studies found: The spread of marijuana use and the opioid epidemic over the past 10 years have affected middle-aged and older Americans. Prescription opioid and benzodiazepine misuse increased older adults’...
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A new study underscores the need for additional research on the effect of medical marijuana laws on opioid overdose deaths and cautions against drawing a causal connection between the two.
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Researchers at NIDA’s Intramural Research Program (IRP) wanted to determine if the incubation of craving would be different in male and female rats and if the effect is stronger after...
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As our communities, healthcare systems, and government agencies join in the effort to reverse the epidemic of opioid overdoses and solve the opioid crisis, it is not enough to focus...
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This research: Adds to research showing that nicotine and cannabis have interactive effects on brain structure and function. Suggests that specialized treatment interventions may be appropriate for people who use...
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In the first half of 2019, we have lost two researchers whose work in neuronal functioning and signaling helped revolutionize our understanding not only of the neurobiology of drug use...
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People with cannabis dependence have changes in neural circuitry in brain regions related to reward processing, habit formation, and psychopathology. These changes in neural circuitry may provide a useful marker...
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In a new animal study, scientists at NIDA’s Intramural Research Program have demonstrated that cocaine use profoundly disrupts these teaching signals.
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In 2017, Dr. Linda Dwoskin applied to NIDA's Grand Opportunity for Medications Development program for support to continue her quest to develop the first-ever medication to reduce craving and relapse...
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Growing evidence in animal studies documents bidirectional signaling between the brain and immune system in the development of behavioral and physical health problems.
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People addicted to heroin and other opioids experience withdrawal when they discontinue or no longer have access to these drugs. Scientists at NIDA’s Intramural Research Program (IRP) wanted to learn...
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One of the major challenges in health science today is that not enough patients participate in clinical trials and other studies. Without volunteers willing and able to participate in studies...
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This research: Revealed associations between nicotine, alcohol, and marijuana use during two periods of adolescence and smaller gray matter volume in two brain areas at age 25. Supports a hypothesis...
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Scientists at NIDA's intramural research labs in Baltimore, Maryland have shown that discriminative stimuli can control the incubation of drug craving, even in the absence of conditioned stimuli.
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This study reported: Prisoners who received methadone maintenance treatment (MMT) during incarceration were more likely than prisoners who did not receive MMT to engage in the treatment after being released...
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This study reported: Interim treatment with buprenorphine significantly improved the psychiatric symptoms of people awaiting comprehensive treatment for opioid use disorder (OUD). Buprenorphine treatment, even without concurrent psychosocial counseling, may...
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Some NIDA-funded scientists have just published findings in the journal Science showing the development of a new, groundbreaking chemogenetics technology for modulating brain function in a remote, precise and ultra-sensitive...
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The NIH HEAL (Helping to End Addiction Long-term) initiative is helping to fund an ambitious research project called the HEALthy Brain and Child Development (HBCD) study. This study, which will...
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NIDA-supported researchers have shown that increased levels of a single protein in the brain's reward center are indispensable for producing some of cocaine's addiction-like effects in animals. Their findings highlight...
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This research shows: An experimental compound with a dual action at two opioid receptors may provide powerful pain relief without many of opioids' harmful side effects. The compound may also...