Punitive policies around drugs contribute to the overwhelming stigma against people with addiction
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Research Highlights
Preventive Interventions Delivered in Childhood May Reduce Substance Use Over Two Generations
Children of intervention recipients showed improved developmental functioning before age 5, as well as fewer problem behaviors; better academic, cognitive, and emotional skills; and less risk behavior from ages 6...
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Using Alcohol and Marijuana Together Exacerbates Negative Consequences in Young Adults
Simultaneous alcohol and marijuana use is associated with both increased alcohol consumption and greater negative consequences.
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Substance use disorders can increase the risk for becoming severely ill from COVID-19, making vaccinations vital.
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Economic Modeling Shows Optimal HIV-Reduction Interventions Depend on the Location
Researchers identified optimal intervention combinations for six cities (one-quarter of all people with HIV in the U.S.).
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Medication Treatment of Opioid Use Disorder Can Protect Against Overdose Death
Fewer overdose deaths occurred among adults treated with opioid agonist medications than among those not treated with medication.
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New guidance for researchers establishes a standard THC unit of 5 milligrams.
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A public health approach to drug addiction is critical for population well-being and health equity
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Childhood Caffeine Exposure May Negatively Affect Cognitive Functioning
For most assessed cognitive functions, the negative correlation remained after controlling for age, gender, socioeconomic status, and sleep.
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Mourning the Loss of a Great Addiction Pioneer
Remembering Dr. Mary Jeanne Kreek, a great addiction pioneer and longtime NIDA grantee.
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Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse
Inhibition of KORs using a short-acting selective antagonist significantly prevented escalation of cocaine intake in rats during chronic exposure and during re-exposure after withdrawal.
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Awareness and Use of Pre-Exposure Prophylaxis for HIV Rise in At-Risk Groups, But Not Enough
Use of pre-exposure prophylaxis to prevent contracting HIV increased among men who have sex with men from 2013 to 2017.
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NIH Director Francis Collins announces UNITE, an NIH-wide initiative to end structural racism in biomedical science
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Using Smartphone Apps to Reach Gay and Bisexual Men at Risk for HIV
Finding better ways to reach people at higher risk of HIV for testing and engagement with HIV prevention and treatment services is a critical component of a public health response...
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Disrupting Cocaine Memories Prevents Return to Cocaine Use in Rats
Preventing cocaine memories from re-strengthening in an unstable period following retrieval attenuates cocaine seeking.
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Inherent in the mission of NIH is that biomedical research and its application can and should benefit all people
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Human Opioid Exposure Can Be Measured Using Wastewater
Using robotic technology, local levels of opioid metabolites can be measured in wastewater from individual manholes
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Co-located HIV Services Can Help Women Who Inject Drugs Access PrEP, Study Shows
Daily, PrEP (pre-exposure prophylaxis medication), is proven to prevent HIV transmission from injection drug use or sex.
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Skewed Opioid Prescribing Patterns in the United States—A Few Providers Prescribe a Large Proportion of Opioids
Only 1 percent of the providers who prescribe opioids account for almost half of all opioid doses prescribed and one-quarter of opioid prescriptions written.
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ADAPT-2 Trial Results Deliver a Breakthrough in Long Search for Methamphetamine Use Disorder Medication
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A combination of bupropion and naltrexone successfully reduced methamphetamine use
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People With SUDs Have Increased Risk for COVID-19 and Worse Outcomes
People with a substance use disorder (SUD) at any time in their lives are 1.5 times more likely to contract COVID-19 than those without an SUD, and those with a...
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Substance Use Status Important When Developing HIV Therapies
Animal studies suggest that subjects with HIV who suffer from opioid use disorders may have higher viral reservoirs in the central nervous system than non-opioid users.
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Patients in treatment for opioid use disorder (OUD) who were more comfortable making decisions when they did not know the probability of outcome had a higher risk of using opioids...
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Unraveling neuroHIV in the Presence of Substance Use Disorders
These reviews address how each of these addictive substances and HIV individually or collectively affect the immune system and subsequent clinical and behavioral outcomes
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NIDA-funded research aims to help understand teen drug use and its effects
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A specific collection of neurons in the basolateral amygdala, a brain region crucial for affect, was active when mice experienced pain. Deactivating this collection of neurons resulted in a loss...
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Elite Controllers May Hold Key to an HIV Cure
"Science" Magazine Breakthrough of the Year Runner Up for 2020
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On World AIDS Day, Celebrating Scientific Advances and Confronting the Complexities of HIV and Substance Use
We applaud the substantial strides made, while recognizing the challenges that need to be addressed.
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HIV and Methamphetamine Use: Double Jeopardy for Transmission of the Novel Coronavirus.
The authors suggest that co-occurring methamphetamine use and HIV present a double jeopardy for COVID.
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There is an alarming increase in deaths involving the stimulant drugs methamphetamine and cocaine.
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