This study showed that rats will forgo heroin and methamphetamine in favor of spending time with another rat. It also highlights the importance of incorporating voluntary choice between drugs and...
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Latest from NIDA
New findings could lead to reduced replication of the HIV virus
In this study, NIDA-funded scientists found that the HIV RNA genome has two previously unknown types of RNA marks.
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Teens who misuse medicines get them from multiple sources
Two NIDA-funded studies have found that adolescents using multiple sources for prescription medications are at high risk for other substance use.
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Co-prescribing naloxone in Medicare Part D increases
A study found that overall national rates for naloxone co-prescription along with any opioid among Medicare Part D patients increased from 1.5 per 1000 patients receiving opioid prescriptions in 2016...
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THC Exposure in Adolescence Disrupts Brain Maturation in Animals
A NIDA-supported study may help explain observed links between adolescent marijuana use and vulnerability to psychiatric disorders.
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First time drug use more common in summertime
Government surveys showed that in 2017, an estimated three million people tried marijuana for the first time, just over a million tried cocaine, close to 800,000 tried LSD, and close...
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Parenting programs lead to healthier behaviors
A study conducted among 517 youth in the rural areas of the southeastern United States demonstrates the effectiveness of a parenting enhancement program in both preventing drug use and obesity...
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NIH establishes network to improve opioid addiction treatment in criminal justice settings
The National Institutes of Health will award 12 grants to form the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder (OUD)...
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Effectively delivering OUD treatment in the justice system will give individuals with OUD a chance of recovery, and will make a huge difference in reducing the toll of the opioid...
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Similarities between aggressive and addictive behaviors
Scientists from NIDA’s Intramural Research Program show that neural mechanisms that control appetitive aggressive behavior are similar to those that control drug-taking and seeking (relapse), suggesting common neurobiological mechanisms of...
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Diversity and inclusion are paramount in all sectors of society, especially in the sciences. Yet it is a well-known (and frequently lamented) fact that males continue to dominate the speaker...
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Disparities in access to quality treatment play a role in every aspect of health care and health outcomes, and the opioid crisis is no different.
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Drug Use and Its Consequences Increase Among Middle-Aged and Older Adults
Studies found: The spread of marijuana use and the opioid epidemic over the past 10 years have affected middle-aged and older Americans. Prescription opioid and benzodiazepine misuse increased older adults’...
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Prescription opioid misuse in high school linked to later heroin use
A NIDA-funded study suggests that misuse of prescription opioid pain relievers in high school could be linked to heroin use later in life.
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Medical Marijuana Laws and Opioid Overdose Rates
A new study underscores the need for additional research on the effect of medical marijuana laws on opioid overdose deaths and cautions against drawing a causal connection between the two.
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Female reproductive cycle affects cocaine craving in animal study
Researchers at NIDA’s Intramural Research Program (IRP) wanted to determine if the incubation of craving would be different in male and female rats and if the effect is stronger after...
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As our communities, healthcare systems, and government agencies join in the effort to reverse the epidemic of opioid overdoses and solve the opioid crisis, it is not enough to focus...
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Nicotine and Cannabis Have Offsetting Effects on Resting Brain Connectivity
This research: Adds to research showing that nicotine and cannabis have interactive effects on brain structure and function. Suggests that specialized treatment interventions may be appropriate for people who use...
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Study finds increased cannabis use during pregnancy
Cannabis use more than doubled among pregnant women in the United States during the period 2002-2017.
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Remembering Two Neurophysiology Pioneers
In the first half of 2019, we have lost two researchers whose work in neuronal functioning and signaling helped revolutionize our understanding not only of the neurobiology of drug use...
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Cannabis Dependence Is Associated With Changes in Neural Circuitry That May Contribute to Psychopathology
People with cannabis dependence have changes in neural circuitry in brain regions related to reward processing, habit formation, and psychopathology. These changes in neural circuitry may provide a useful marker...
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Project to deter opioid tampering wins 2019 NIDA Addiction Science Award
A 14-year-old’s innovative approach to prevent tampering and misuse of opioid pills won a first place Addiction Science Award at the 2019 Intel International Science and Engineering Fair (ISEF)—the world’s...
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National Institute on Drug Abuse Intramural Research Program Holds Opioid Symposium
The National Institute on Drug Abuse (NIDA) Intramural Research Program will hold a one-day symposium to summarize the most recent advances in opioid research.
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Brief drug use disrupts learning mechanisms in the brain
In a new animal study, scientists at NIDA’s Intramural Research Program have demonstrated that cocaine use profoundly disrupts these teaching signals.
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Narrative of Discovery: The Quest for a Medication To Treat Methamphetamine Addiction, Part 4
In 2017, Dr. Linda Dwoskin applied to NIDA's Grand Opportunity for Medications Development program for support to continue her quest to develop the first-ever medication to reduce craving and relapse...
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The Brain and our Immune System: Working Together
Growing evidence in animal studies documents bidirectional signaling between the brain and immune system in the development of behavioral and physical health problems.
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Scientists identify brain circuits engaged in compulsive heroin use
People addicted to heroin and other opioids experience withdrawal when they discontinue or no longer have access to these drugs. Scientists at NIDA’s Intramural Research Program (IRP) wanted to learn...
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How People with Substance Use Disorders (SUDs) Can Lend a Needed Hand in Addiction Research
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One of the major challenges in health science today is that not enough patients participate in clinical trials and other studies. Without volunteers willing and able to participate in studies...
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Opioid Dose Variability Associated with Overdose
A new study funded by the National Institute on Drug Abuse found that high dose variability increases the odds for an opioid overdose independent of dose alone.
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Research Links Adolescent Substance Use to Adult Brain Volumes
This research: Revealed associations between nicotine, alcohol, and marijuana use during two periods of adolescence and smaller gray matter volume in two brain areas at age 25. Supports a hypothesis...
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