While student smoking rates have declined in recent years, e-cigarette use has risen—an alarming trend, because most vaping devices contain the highly addictive drug nicotine. In this lesson, developed in partnership with Scholastic, students read "How Nicotine Affects the Teen Brain" to understand how nicotine is not only highly addictive, but can also cause lasting effects on their brain. An article and worksheet get students to think critically about the real health risks of nicotine and vaping nicotine. Then students complete the "Vaping Health Risks" presentation activity, to guide them to conduct deeper research into specific vaping risks and help spread the word to their peers.