Adaptation and Implementation of a Community Pharmacy-Based Prescription Drug Monitoring Program Opioid Risk Assessment Tool

A prescription drug monitoring program-based clinical decision support platform, with clinically actionable opioid risk information, is not widely available in the field of community pharmacy. This project will: (1) integrate risky opioid use thresholds established in CTN-0093 into a nationally scalable prescription drug monitoring platform; (2) adapt the platform to direct pharmacy staff in performing confirmatory opioid misuse screening, opioid medication misuse intervention, naloxone dispensation, and warm handoff; and (3) evaluate patient outcomes. To evaluate patient outcomes, our interdisciplinary team will conduct a type-1 implementation mixed methods study using a two-arm parallel group clustered randomized trial to test the platform in a large retail pharmacy chain. This study will also examine facilitators and barriers of platform adoption and continued utilization from corporate partners. Results of this study will facilitate critical advancements for protecting patient health and addressing the national opioid epidemic by leveraging community pharmacy.