Promoting Research with Mothers receiving OUD Treatment; a focus on Equity (PRoMOTE)

The purpose of this study is to prioritize and elevate the voices of women of color who have opioid use disorder (OUD) and are enrolled in the National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN)-0080 Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs) trial. The study will qualitatively explore the perspectives of CTN-0080 participants of color and triangulate findings with interviews of research staff to explore drivers of trial enrollment and treatment adherence. The study will apply mixed-methods to investigate facilitators and barriers to treatment initiation of medications to treat opioid use disorder (MOUD), trial engagement, and study retention in CTN-0080, with a focus on race, racism, and equity. The study will also triangulate interview responses with individual-, site-, and state-level characteristics to identify opportunities for intervention to address stigma, discrimination, and racism in perinatal substance use disorder (SUD) care at individual, interpersonal, and structural levels.