To help applicants navigate the submission process, NIH has compiled an extensive instruction manual (SF424) that provides complete details on filling out the forms that go into a successful application submission. Understanding the application process is critical to successfully submitting your application.
Applicants should use the SF424 instructions, together with the forms and information found in the funding opportunity announcement, to complete the application. The SF424 instructions cover topics such as the required registrations before submission, how to submit and track the application, where to find page limits, R&R budget form requirements, and who to include as senior/key personal.
Annotated Application Form
The funding opportunity and associated application guide remain the official documents for defining application requirements. This annotated form is for the Omnibus SBIR/STTR solicitation and set is meant to complement, not replace, those documents:
For targeted NOFOs, please see additional requirements outline in announcement.
Real-life successful SBIR and STTR applications
Review sample successful applications from the National Institute of Allergy and Infectious Disease (NIAID) and the National Institute on Aging (NIA).
|Funded Company||Application Type||Technology Type||Application Links|
|CareBand||SBIR, Phase I, Original||FDA-regulated therapeutic and diagnostic devices|
|CareBand||SBIR, Phase I, Resubmission||FDA-regulated therapeutic and diagnostic devices|
|Care.coach||SBIR, Phase I, Original||Health IT (not-FDA regulated)|
|Care.coach||SBIR, Phase I, Resubmission||Health IT (not-FDA regulated)|
|BioFire Diagnostics, LLC.||SBIR, Phase I, Original||FDA-regulated therapeutic and diagnostic devices|
|MBio Diagnostics, Inc.||SBIR, Phase II, Original||FDA-regulated therapeutic and diagnostic devices|
|Crossroads Consulting||SBIR, Phase II, Original||FDA-regulated therapeutic and diagnostic devices|
|OP-T-MUNE, Inc.||STTR, Phase I, Original||Pharmaco-Therapeutic (small molecule or biologic)|
|CorticoMetrics||STTR, Fast Track, Original||FDA-regulated therapeutic and diagnostic devices|
|CorticoMetrics||STTR, Fast Track, Resubmission||FDA-regulated therapeutic and diagnostic devices|