Sample Applications for SBIR/STTR

Application Instructions

To help applicants navigate the submission process, NIH has compiled an extensive instruction manual (SF424) that provides complete details on filling out the forms that go into a successful application submission. Understanding the application process is critical to successfully submitting your application.

Applicants should use the SF424 instructions, together with the forms and information found in the funding opportunity announcement, to complete the application. The SF424 instructions cover topics such as the required registrations before submission, how to submit and track the application, where to find page limits, R&R budget form requirements, and who to include as senior/key personal.

Annotated Application Form

The Funding Opportunity Announcement (FOA) and associated application guide remain the official documents for defining application requirements. This annotated form is for the Omnibus SBIR/STTR solicitation and set is meant to complement, not replace, those documents: 

For targeted FOAs, please see additional requirements outline in announcement.

Real-life successful SBIR and STTR applications

Review sample successful applications from the National Institute of Allergy and Infectious Disease (NIAID) and the National Institute on Aging (NIA).

Funded Company Application Type Technology Type Application Links
CareBand SBIR, Phase I, Original FDA-regulated therapeutic and diagnostic devices
CareBand SBIR, Phase I, Resubmission FDA-regulated therapeutic and diagnostic devices
Care.coach SBIR, Phase I, Original Health IT (not-FDA regulated)
Care.coach SBIR, Phase I, Resubmission Health IT (not-FDA regulated)
BioFire Diagnostics, LLC. SBIR, Phase I, Original FDA-regulated therapeutic and diagnostic devices
MBio Diagnostics, Inc. SBIR, Phase II, Original FDA-regulated therapeutic and diagnostic devices
Crossroads Consulting SBIR, Phase II, Original FDA-regulated therapeutic and diagnostic devices
OP-T-MUNE, Inc. STTR, Phase I, Original Pharmaco-Therapeutic (small molecule or biologic)
CorticoMetrics STTR, Fast Track, Original FDA-regulated therapeutic and diagnostic devices
CorticoMetrics STTR, Fast Track, Resubmission FDA-regulated therapeutic and diagnostic devices

Review additional sample application on the NIAID’s and NIA’s website.