Close-up of a lab researcher's gloved hands, while they are holding a test tube and pipette inside a fume hood.
©Getty Images/gevende
  • Ketamine is FDA-approved for use as an anesthetic in humans and animals. A drug made from ketamine, called esketamine, is FDA-approved for treatment-resistant depression. Ketamine has also been illegally manufactured for decades as a recreational drug.
  • Ketamine can cause strong mood and mind effects. People who take ketamine may experience changes in how they perceive reality, including intense feelings of either dissolving into or being entirely disconnected from their environment.
  • NIDA researchers are studying ketamine as a potential clinical treatment for substance use disorders.

Latest from NIDA

Find More Resources on Ketamine