NIDA Genetic Consortium Meetings & Abstracts

May 2023 Meeting


The Genetics and Epigenetics Cross-Cutting Research Team of the National Institute on Drug Abuse invites you to attend the May 16-17, 2023 NIDA Genetics and Epigenetics Cross-Cutting Research Team Meeting at Natcher Auditorium on the NIH Campus in Bethesda, MD. This is an in-person meeting. We expect to have more than 215 scientific presentations.

Please register for the meeting here:

Meeting Dates and Times

  • Tuesday, May 16th: - 9:00 a.m. to 5:30 p.m.
  • Wednesday, May 17th  - 9:00 a.m. to 5:00 p.m.

Agenda and Meeting Abstracts

May 16 – Keynote (9:15 am – 9:45 am)
TimeFirst NameLast NameEmailAbstract Title
9:15AndreToussaintat3658@columbia.eduUnderstanding Substance Abuse from Scientific and Human Perspectives
May 16 – Session 1 (9:45 am – 11:00 am) - Single cell transcriptional and chromatin profiling of brain reward structures identifies new candidate targets in substance use disorders Eric Nestler and Jeremy Day, Chairs
TimeFirst NameLast NameEmailAbstract Title
9:45KristenMaynardkristen.maynard@libd.orgIntegrated single cell and spatial transcriptomic approaches for defining the molecular anatomy of reward circuitry in the human brain
10:00MarineSalerymarine.salery@mssm.eduCapturing and profiling cocaine-recruited Arc neuronal ensembles encoding drug-context associations in the Nucleus Accumbens.
10:15JenniferTuscherjtuscher@uab.eduMultiomic profiling of the rat nucleus accumbens reveals cell-type specific chromatin remodeling and transcriptional alterations after cocaine experience
10:30BenjaminReinerbcreiner@pennmedicine.upenn.eduSingle nuclei transcriptomic analysis of rat nucleus accumbens reveals cell type-specific patterns of gene expression associated with volitional morphine
May 16 – Special Presentation (11:00 am – 11:10 am)
TimeFirst NameLast NameEmailAbstract Title
11:00AnitaBandrowskibandrow@gmail.comRRIDs and where they fit into known standards such as the ARRIVE 2.0 guidelines
May 16 – Session 2 (2:00 pm – 3:00 pm) Artificial Intelligence (AI) Application in Genetics and Epigenomics Carl Lin and Sara Mostafavi, Chairs
TimeFirst NameLast NameEmailAbstract Title
2:00CarlLinzlin@mclean.harvard.eduHistory and Application of Artificial Intelligence: Its Turn for Genomics
2:00SaraMostafavisaramos@cs.washington.eduSequence-based deep learning models for predicting molecular phenotypes
2:15HongyangLiHongyang.Li@ibm.comAsymmetric Predictive Relationships Across Histone Modifications
2:30AndreasPfenningapfenning@cmu.eduFine-mapping candidate neuropsychiatric regulatory variants using cell type-aware comparative genomics
May – 16 Session 3 (4:30 pm – 5:20 pm) - Short Talk Presentations
TimeFirst NameLast NameEmailAbstract Title
4:30AlexanderHatoumashatoum@wustl.eduMultivariate genome-wide assocation meta-analysis of 1 million subjects identifies loci underlying multiple substance use disorders
4:40JeffreyHatfieldjshatfi@g.clemson.eduCocaine Preference in the Drosophila melanogaster Genetic Reference Panel
4:50ChelsieBenca-Bachmanchelsie.benca@emory.eduAdditive Genetic and Interactive Effects on Alcohol Problems and Traumatic Experiences Among African Americans
4:55Xiufang (Nadine)Guoxguo@mail.ucf.eduDevelopment of an iPSC-preBötC neuron opiate overdose and recovery multi-organ platform
5:00JenniferKelschenbachjennifer.kelschenbach@mssm.eduMorphine dependence accelerates HIV-associated neurocognitive impairment in EcoHIV infected mice
5:05SalmaMajidmajidsn@nih.govRecurrent and non-recurrent copy number variants in American Indian tribes with substance use disorders
5:10FreddysonMartinez-Riverafreddyson.martinez-rivera@mssm.eduCellular and transcriptional contributions of the nucleus accumbens in transferring extinction-based memories
5:15EvaristusNwuliaenwulia@howard.eduLinking Cannabis Use Disorder, Long-noncoding RNA and Olfactory Structure and Function
May 17 – Session 4 (9:00 am – 10:15 am) - Non-Cannonical regulation of gene-expression by drugs with addictive properties Elizabeth Heller and Zhzhu Zhang, Chairs
TimeFirst NameLast NameEmailAbstract Title
9:00ElizabethHellereheller@pennmedicine.upenn.eduCocaine regulation of alternative splicing via changes in histone postranslational modifications.
9:15ZijunWangzjwang@ku.eduDNA damage and repair processes are involved in opioid addiction
9:30ZhuzhuZhangzhuzhuzhang@uchicago.eduEpigenomic remodeling at single cell resolution in cocaine self-administration in mice
9:45BaDoiPhanbadoi.phan@pitt.eduWhole-animal massively parallel reporter assay dissects the region-specific transcriptional impact of human addiction genetic variants
May 17 – Session 5 (1:15 pm – 2:30 pm) - The Role of Behavioral Undercontrol in Mediating Genetic Risk for Substance Use Disorders Abraham Palmer and Danielle Dick, Chairs
TimeFirst NameLast NameEmailAbstract Title
1:15HollyPooreholly.poore@rutgers.eduCharacterizing the Genetic Overlap between Externalizing Phenotypes and Substance Use Disorders
1:30SandraSanchez-Roigesanchezroige@ucsd.eduCADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice
1:45HudaAkilakil@umich.eduSelectively Breeding for Temperament and Vulnerability to Addiction: A Genetic, Genomic and Neural Characterization of Behavioral Undercontrol and Overcontrol.
2:00MichaelSheldonmichael.sheldon@sampled.comBiobanking as a Foundational Component of NIH Research: The NIDA Center for Genetic Studies Provides A Critical Resource for Research into the Genetics and Epigenetics of Substance Abuse
May – 17 Session 6 (4:00 pm – 4:50 pm) - Short Talk Presentations
TimeFirst NameLast NameEmailAbstract Title
4:00AmritKoiralaamrit.koirala@bcm.eduDeconvolution of microRNA/mRNA Networks in Brain Regions Impacted by Cocaine Use Disorder to Develop a Mechanistic Biosignature for Pharmacotherapy Response
4:10VivekPhilipVivek.Philip@jax.orgEnumeration and visualization of differential gene co-expression response to cocaine
4:20JanitzaMontalvo-Ortizjanitza.montalvo-ortiz@yale.eduDeciphering the role of DNA hydroxymethylation in substance use disorders
4:25MadhurBainSinghsinghm18@vcu.eduExamining Bidirectional Causal Effects between Smoking and DNA Methylation using Epigenetic Mendelian Randomization Analyses
4:30AlyssaWilsonalyssa.wilson@mssm.eduIdentifying Cell-Type-Specific Transcriptional Changes in Midbrain in the Context of Substance Use Disorder and Long-Term HIV Infection: A Cohort Study at the Manhattan HIV Brain Bank
4:35FrancescaTeleseftelese@health.ucsd.eduAnalysis of single nuclei RNA-seq from the nucleus accumbens of heterozygous reeler mice exposed to THC during adolescence suggests a link between THC exposure, Reelin signaling, and vulnerability to human psychiatric disorders
4:40JaredBagleyjbagley@binghamton.eduNeuron navigator 1 regulates the self-administration of cocaine
4:45LauraSabaLaura.Saba@cuanschutz.eduMulti-omic single nuclei data provide insight into the cellular origin of whole brain coexpression patterns related to Oprm1
May 16 – Poster Session A (11:10 am – 12:40 pm)
Poster #First NameLast NameEmailAbstract Title
1ArpanaAgrawalarpana@wustl.eduThe Psychiatric Genomics Consortium Substance Use Disorders Working Group (PGC-SUD): An Update
2SchahramAkbarianschahram.akbarian@mssm.eduSingle Nucleus Transcriptomic Profiling of Human Ventral Midbrain Reveals Widespread Activation of Multiple Glial Subtype
3MuhammadArshadmuhammadwaqar.arshad@yale.eduSubstance Abuse in Pakistan: Clinical Issues and Research Opportunities
4Bao-ZhuYangbao-zhu.yang@yale.eduInter-Linking the Developmental Brain Transcriptome and GWAS Risk Variants Revealed Neural Circuits Prognostic of Nicotine Use Severity
5DavidAshbrookdashbrook@UTHSC.eduGood wine and old data get better with age: New insights on gene-by-environment effects of drugs of abuse in mice using
6ChristopherBakerchristopher.baker@jax.orgGenetic variation influences cell specific cis-regulatory landscape in the mouse striatum
7MadelynBakermrb4002@med.cornell.eduEpigenetic representation of cocaine-context association in the dorsal dentate gyrus of male mice
8BritahnyBaskinbritty@bu.eduPremorbid addiction model traits and cocaine stimulant sensitivity in spontaneously hypertensive rat (SHR) substrains
9JacobBeierleJacob.Beierle@jax.orgA high-throughput machine vision-based univariate scale for pain and analgesia in mice
10AritraBhattacherjeewritetoab@gmail.comDecoding molecular organization of the brain reward circuit for understanding mechanisms of drug addiction Mediation Analysis of Genetic Variants, Brain Connectome and Nicotine Addiction
12FatahKashanchifkashanc@gmu.eduRetroviral infection of human neurospheres and use of stem cell EVs to repair cellular damage
13KaseyBridakbrida@uab.eduReelin protein marks cocaine-sensitive Drd1+ medium spiny neurons and modulates medium spiny neuron physiology and behavioral response to cocaine
14RussellBrownBROWN1@mail.etsu.eduAnalysis of the enhanced rewarding effects of nicotine and underlying neuroplasticity mechanisms in a heritable model of drug abuse vulnerability in psychosis
15CalebBrownecaleb.browne@mssm.eduTranscriptome profiling of the brain’s reward circuitry in heroin self-administration identifies a ventral hippocampus gene network related to relapse susceptibility
16EdwardBrowneepbrowne@email.unc.eduDefining the impact of cannabis use on immune cell phenotypes and the latent viral reservoir in people with HIV.
17CamronBryantcamron@bu.eduSpectrotemporal USV profiles during neonatal opioid withdrawal in FVB substrains, Zhx2-edited BALB/c substrains, and outbred CFW mice
18JasonBubierJason.Bubier@jax.orgA Tale of Two Opioids: The Genetics of Opioid Induced Respiratory Depression in Response to Fentanyl and Morphine in Mice.
19BelleBuzzibuzzib@vcu.eduNicotine reward and preference in C57BL/6J and C57BL/6N mouse strains
20Jean LudCadetjcadet@intra.nida.nih.govCompulsive methamphetamine intake and abstinence in the presence of punishment are associated with differential hydroxymethylation of miRNAs in the rat nucleus accumbens
21CaliCalarcoccalarco@som.umaryland.eduMitochondrial gene ontology pathways and transcriptional regulators impacted by cocaine in C57Bl/6 mice
22RianneCampbellrcampbell@som.umaryland.eduBaseline Characterizations of Novel D1R-CRISPRa and A2A-CRISPRa Mouse Lines
23JavanCarterJCarter@rti.orgIdentifying novel genes and pathways associated with opioid overdose death via meta-analysis of differential gene expression.
24SamanthaCheeksscheeks@uci.eduCannabidiol Attenuates Nicotine Self-Administration and Withdrawal Symptomology in Mice
25JixinChenchenj@ohio.eduA single-molecule FRET data fitting package for DNA folding kinetic study
26YongChenchenyong@rowan.eduInferring Memory-related Regulatory Modules in Engram Cells by Deep-learning and scRNA-seq Data epigenetic alterations converge on key genes linked to opioid overdose
28DanielWoodwoodda@musc.eduHDAC5 intrinsic enzymatic activity limits drug-seeking behavior
29SantiagoCuestasantiago.cuesta@rutgers.eduGut Microbiota Composition Modulates Cocaine-Induced Neurobehavioral Plasticity
30EamonnDuffyEamonn.Duffy@colorado.eduCharacterization of thermal and mechanical sensitivity in select strains of the Hybrid Rat Diversity Panel
31SorenEmersonsoren.d.emerson@vanderbilt.eduLysine acetyltransferase KAT2a is a novel cocaine-recruited epigenetic regulator in the nucleus accumbens
32DanFabrisdan.fabris@uconn.eduInvestigating epitranscriptomic communications between HIV-1 infection and neuromodulator response in different CNS cells
33FangFangffang@rti.orgA DNA methylation-based classifier for lifetime cannabis use
34J. AdamFieldsjafields@health.ucsd.eduEffects of cannabinoids on phenotype of patient monocyte-derived macrophages vary by cannabis use patterns
35ZoeFigueroazoe.figueroa@email.ucr.eduAstrocytic contributions to chronic methamphetamine induced neuroinflammation and disease
36PrescillaGarcia-Trevizopjg5435@psu.eduLong-term Effects of Adolescent Nicotine Exposure on Sensitivity and Cotinine in the Diversity Outbred Mouse Population.
37PaigeLemenplemen1@uthsc.eduAdolescent Social Isolation Increases Vulnerability to Voluntary Opioid Consumption in Adulthood in Rats
38MuditTyagiMudit.Tyagi@jefferson.eduCocaine by co-stimulating NF-kB, NFAT, and AP-1 enhances CD4+ T-cells metabolism; thus, sensitizes partially active cells for HIV infection
39Min-AeSongsong.991@osu.eduEpigenetic Aging in the Human Lung: Focus on Smoking and Vaping
May 16 – Poster Session B (3:00 pm – 4:30 pm)
Poster #First NameLast NameEmailAbstract Title
1VivekSwarupvswarup@uci.eduInvestigating multi-omic Mechanisms Underlying Opioid Addiction Vulnerability: A Multi-Omics Study
2ColinHodgkinsonchodg@mail.nih.govAlcohol and stress additively accelerate epigenetic cellular age of Cocaine Use Disorder: A new paradigm to study the impact of environmental exposures in Substance Use Disorders
4BenjaminGrissomBGrissom@som.umaryland.eduHeroin-induced genomic regulation of ventral pallidum and nucleus accumbens neuron subtypes
5PetarGrozdanovpetar.grozdanov@ttuhsc.eduThe role of alternative polyadenylation in a TLR3-mediated mouse model of escalated alcohol consumption
6HongshengGuihgui1@hfhs.orgBivariate relationship between opioid use disorder and suicide attempts despite mental health
7MeganHagenauerhagenaue@umich.eduThe Brain Data Alchemy Project: Teaching Research Reproducibility and Discovery Science While Mining Gold from Archived Genomics Data
8NikhilHajirnisnhajirnis@som.umaryland.eduEpigenomic editing of nucleus accumbens neuron subtypes using the CRISPR-Cas12f derived system
9PeterHamiltonpeter.hamilton@vcuhealth.orgSynthetic transcription factors, delivered to mouse nucleus accumbens, dysregulate drug-specific transcription and behaviors of Sirt3 induced by HIV gp120 with morphine in neuropathic pain, is mediated by H3K27me3 in the spinal cord
11EmilyHartwellEmily.Hartwell@pennmedicine.upenn.eduPerformance of a polygenic risk score for depression in a deeply phenotyped sample
12YingHeyhe@midwestern.eduEpigenetic regulation of opioid dependence by microRNAs
13ElaineHebda-Bauerhebda@med.umich.eduBioenergetic-Related Gene Expression in the Hippocampus Predicts Internalizing vs. Externalizing Behavior in a F2 Cross of Selectively-Bred Rats
14Ming-FenHoho.mingfen@mayo.eduEpigenetic Regulation of GABA Catabolism in iPSC-derived Neurons: the Role of FGF21
15LeanneHoltleanne.holt@mssm.eduElucidation of the astrocyte-specific transcriptome following cocaine self-administration
16SpencerHuggettshuggett91@gmail.comIn Silico Genetic & Neuromolecular Drug Repurposing for Opioid Use Disorder
17AlvinJefferyalvin.d.jeffery@vanderbilt.eduDetecting Opioid Use Disorders in the Electronic Health Record to Support Genetic Studies: Adaptation of the Addiction Behaviors Checklist
18ThomasJhoujhou@musc.eduHeritability and GWAS analyses of punishment sensitivity and cocaine avoidance in HS rats
19KanShaokshao@indiana.eduDose-Response Analysis to Advance Gene and Pathway Identification for Risk Estimation of Substance Use Disorder
20GuochunJiangjianggc@gmail.comEpigenetic regulation of a persistent HIV reservoir in human brain myeloid cells despite durable ART
21EmmaJohnsonemma.c.johnson@wustl.eduCross-disorder analysis of cannabis use disorder and schizophrenia reveals convergent and divergent genetic influences
22YonwooJungyonwoo.jung@nih.govMitochondrial Dysfunction and Oxidative Stress: Conserved Functional Phenotypes in Cocaine Addiction across Multiple Brain Regions
23MarcusKaulMarcus.Kaul@medsch.ucr.eduMethamphetamine promotes in macrophages stimulated with LTR mimic ssRNA40 expression of HIV-regulating lncRNA HEAL and pro-inflammatory factors but suppresses the interferon response
24PanjunKimpkim11@uthsc.edu3D Chromatin Interaction Data Facilitates de novo Genome Assembly and Identifies Promoter-Enhancer Interaction in the PFC of Rats
25CassandraKooikerckooiker@uci.eduGenetic tagging uncovers a role for the thalamic paraventricular nucleus in mediating aberrant reward behaviors following adverse experiences early in life
26BrittanyKuhnkuhnb@musc.eduNetwork-based clustering approach models multi-symptomatic opioid use disorder vulnerability
27AshleyKumaravkumar@ucsd.eduTranscriptional initiation profiling of primary brain cells to study stimulus-dependent enhancer activity
28ValeriaLallaivlallai@uci.eduTHC- and Nicotine-Induced Changes in Central and Peripheral Extracellular Vesicle RNA Cargo
29EvaLancasterEva.Lancaster@vcuhealth.orgExamining polygenic risk score by environment interaction on the relationship between interpersonal violence exposure and alcohol use in an ancestrally diverse college cohort
30PaigeLemenplemen1@uthsc.eduOpiate responses are controlled by interactions of Oprm1 and Fgf12 loci in rodents: Correspondence to human GWAS findings
31MichaelLeonemleone@andrew.cmu.eduSpinal cord neuronal subtypes conserved across species are genetically implicated in chronic pain disorders
32DongmeiLiDongmei_Li@urmc.rochester.eduLongitudinal changes in expression profile of urine exosomal epigenetic microRNAs in exclusive electronic cigarette adult users
33XiaoyuLiangxiaoyuliang@msu.eduDNA Methylation-Based Telomere Length Is Associated With HIV Frailty and All-Cause Mortality
34CarlLitifclitif@uwyo.eduIdentifying reward-specific transcriptomes underlying polyreward seeking ensembles in the nucleus accumbens core and prelimbic cortex
35ShirelleLiuliu00459@umn.eduDifferential gene expression and epigenetic regulation in the medial prefrontal cortex of rats showing vulnerability to opioid addiction
36JenniferLoftisloftisj@ohsu.eduPlasma extracellular vesicles and their miRNA cargo as biosignatures for neuropsychiatric impairments in methamphetamine use disorders
37RyanLoganRyan.Logan@umassmed.eduElevated DNA damage and inflammatory markers in specific striatal cell types associated with opioid use disorder using single nuclei RNAseq in human postmortem brain
38FalkLohofffalk.lohoff@nih.govAdditive Effects of Stress and Alcohol on Epigenetic Aging
39SamikkannuThangavelthangavel@tamu.eduEpigenetic signature of N-terminal acetyltransferases role in HIV-Neuropathogenesis
May 17 – Poster Session C (10:15 am – 11:45 am)
Poster #First NameLast NameEmailAbstract Title
1AliceMinAlice.Min@mountsinai.orgA novel humanized mouse model to track active and latent CNS HIV-1 infection and to test therapeutic interventions, measurement error and pleiotropy robustness in twin design extensions to Mendelian randomization
3PaigeLemenplemen1@uthsc.eduOxycodone oral self-administration in inbred rats identifies different patterns of vulnerability
4AndrewLombardianlo5057@colorado.eduRole of GSCAN Identified Genes in the Astrocytic Response to Nicotine
5ShahrdadLotfipourshahrdadlotfipour@me.comFunctional Role of a Human 3'UTR Alpha6 Nicotinic Receptor Polymorphism (rs2304297) in Adolescent Substance Use
6QingLulucienq@ufl.eduKernel Neural Networks for Analyzing Large-scale Substance Use Disorders Genetic Data
7WilliamLynchwlynch@bu.eduValidating Zhx2 in oxycodone metabolite (oxymorphone) brain concentration and behavior via reciprocal gene editing and viral manipulation of gene expression in BALB/c substrains
8TianzhouMatma0929@umd.eduBayesian indicator variable selection for multivariate response with application to multi-trait fine mapping
9ScottMackeymsmackey@uvm.comENIGMA Addiction: Neuroimaging Biotypes Supported by Gene Enrichment Analysis
10RajtarunMadangopalrajtarun.madangopal@nih.govIn vivo labeling and molecular characterization of cocaine memory-specific active neurons using the photo-convertible calcium integrator CaMPARI2
11TravisMallardtmallard@mgh.harvard.eduLimited evidence for a general dimension of impulsivity across genomic, transcriptomic, and neuroanatomical levels of analysis
12LisaMaturinlmaturin@health.ucsd.eduThe Addiction Biobanks: : Three repositories of biological samples from genetically characterized outbred rats that exhibit compulsive-like escalation of cocaine, oxycodone, and alcohol self-administration.
13NicolaMicalinicola.micali@yale.eduThe effect of prenatal cannabinoid exposure on developing primate cerebrum
14MelyssaMintomminto@rti.orgTissue-Specific DNA Methylation Signatures of Alcohol Use Disorder in Human Brain
15SuzanneMitchellmitchesu@ohsu.eduLessons learned in creating selected lines for high and low delay discounting
16MaheshMohanmmohan@txbiomed.orgDelta-9-Tetrahydrocannabinol:Cannabidiol combination counteracts colonic epithelial and blood-brain barrier dysfunction in SIV-infected rhesus macaques on combination anti-retroviral therapy
17KaterynaMurlanovakmurlano@buffalo.eduLoss of astrocytic mu opioid receptors exacerbates aversion associated with morphine withdrawal in mice: a role for mitochondrial respiration
18RandyNelsonrandy.nelson@hsc.wvu.eduLight at Night Drives Sex-Specific Increases in Fentanyl Reward-Related Behaviors
19AbrahamPalmeraap@ucsd.eduRATTACA: a new paradigm for examining genetic correlations in outbred rats
20RohanPalmerRohan.Palmer@Emory.eduConserved Co-expression Signatures of Chronic Alcohol Consumption across Species
21ClarissaParkercparker@middlebury.eduGenetic variation and heritability of negative affective withdrawal from cocaine in the CC/DO founder mouse strains
22GitaPathakgita.pathak@yale.eduEpigenetic profiles of latent classes for polysubstance use disorder
23JackPatteejack.pattee@cuanschutz.eduAdjusting for cis-regulatory variation in gene expression data can improve biological network analysis in model organisms
24QianPengqpeng@scripps.eduPleiotropic Loci for Cannabis Use Disorder Severity in Multi-Ancestry High-Risk Populations
25IngaPeteringa.peter@mssm.eduHigh Content Transcriptomics Screen to Explore Pathway Crosstalk between Morphine and Antiretroviral Therapy Drug Combinations
26AmandaGentryAmanda.Gentry@vcuhealth.orgMachine Learning to Predict Alcohol Consumption From Blood-Based Biomarkers
27RobertPhillipsrphill3@uab.eduDistinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine
28BryanQuachbquach@rti.orgTranscriptome-wide association study for frequent cocaine use identifies gene dysregulation in CD4+ T cells linked to immune response and cancer pathways QTL analysis identifies genetic variants that influence H3K27ac in opioid overdose cases.
30YumnaRahmanrahmany@vcu.eduInfluence of Genotype and Sex on Oral Nicotine Consumption in Founder Strains of Diversity Outbred Mice in Gene Regulation Across Neurons from Seven Different Brain Regions
32DavidRootDavid.Root@Colorado.EDUVentral tegmental area glutamate neurons establish a mu-opioid receptor gated circuit to mesolimbic dopamine neurons and regulate opioid-seeking behavior
33AdrianRothenfluhadrian.rothenfluh@hsc.utah.eduBitter gustatory perception protects Drosophila from escalating cocaine consumption preference.
34ErickSaldesesaldes@miners.utep.eduNovel genetic loci interacting with social environment for dysfunctional inhibitory control
35DanielleSambodanielle.sambo@nih.govDifferential effects of prenatal alcohol exposure on brain growth in a mouse model for fetal alcohol spectrum disorder expressed genes in Opioid Use Disorder are enriched amongst genes with brain region specific regulatory activity
37JiangwenSunjsun@odu.eduTraining Deep Neural Networks Predicting DNA Methylation to Elucidate Genetic Associations in Substance Use Disorders
May 17 – Poster Session D (2:30 pm – 4:00 pm)
Poster #First NameLast NameEmailAbstract Title
1SandraSanchez-Roigesanchezroige@ucsd.eduMulti-ancestry meta-analysis of tobacco use disorder based on electronic health record data prioritizes novel candidate risk genes and reveals associations with numerous health outcomes
2PietroSannapsanna@scripps.eduUnraveling the interplay between neuroHIV and substance abuse with systems biology to shed light on novel druggable targets.
3KatherineSavellkatherine.savell@nih.govDevelopment of multipleXed Population Selection and Enrichment single nuclei RNA-sequencing (XPoSE-seq) to characterize neuronal ensembles in cocaine relapse
4Randal AlexSerafinialex.serafini@icahn.mssm.eduNovel Oxycodone Paradigm Highlights Mesocorticolimbic Mechanisms Underpinning Withdrawal-associated Behaviors with and without Chronic Pain
5MaritSolheim-Wittmarit@alpha-element.comResilience, resourcefulness and self-leadership: Evaluation of a self-management program and novel conceptual framework of Vitality Type patterns in behavior and communication
6AkhilSharmaakhilsharma@wayne.eduComparing Responses of the Nucleus Accumbens and Ammon’s Horn to Methamphetamine Neurotoxicity mining of biomedical literature: Applications for the drug repurposing for the treatment of HIV-Associated Neurocognitive Disorder.
8OmarSoler-Cedeñoomar.soler-cedeno@nih.govBrain CB2 receptor: a new therapeutic target for treating opioid use disorders, major findings from a new CB2-KO-eGFP reporter mouse line
9SheetalSreeramsxs2286@case.eduInduced pluripotent stem cells (iPSCs) derived cerebral organoids to model the impact of methamphetamine exposure on HIV latency.
10ChaitanyaSrinivasancsriniv1@cs.cmu.eduRegulatory variation in D1/D2 co-expressing medium spiny neurons is suggested to predispose addiction-related traits
11JerryStitzelstitzel@colorado.eduQTL Mapping of Genetic Modifiers of Oral Nicotine Consumption in Chrna5 Null Mutant Mice
12KyleSullivansullivanka@ornl.govHeroin overdose-associated transcriptional and epigenetic alterations in the orbitofrontal cortex concentrate in GABAergic interneurons and provide insight into cell type-specific regulatory response
13JiangwenSunjsun@odu.eduAnnotating Genetic Variants by Training Deep Neural Networks to Predict Multiple Epigenomic Events in Brain via Effective Multi-task Learning
14MakotoTaniguchiTaniguch@musc.eduA long non-coding enhancer RNA regulates NPAS4 in the NAc to control drug reward-conditioned behavior
15LisaTarantinolisat@med.unc.eduGenetic mapping of initial locomotor sensitivity to cocaine in two divergent Collaborative Cross inbred mouse strains
16IrisTitosiris.titos@utah.eduMechanisms of diet modulating experience-dependent amphetamine preference
17JillTurnerJill.Turner@uky.eduPhenotyping Individual Differences in Escalation of Fentanyl Self-Administration in Sprague-Dawley Rats. 
18DavidVandenberghdjv4@psu.eduHyper-Variable Number of Tandem Repeats in Intron 8 of the Human Dopamine Transporter Gene (SLC6A3)
19ArvindVenkataramanavenkata@uw.eduA genome-wide association study of methamphetamine use among people with HIV
20ThiagoViolathiago.wendt.viola@gmail.comThe effects of maternal cocaine use during pregnancy in pediatric epigenetic clocks and methylation risk scores in humans Sequencing Study of Alcohol Use Disorder in 1,668 European Americans and 1,547 African Americans
22XuWangxuwang@temple.eduActivation of Toll-like receptor 3 by poly (I:C) inhibits HIV infection of human iPSC-derived microglia
23TaoWuTao.Wu@bcm.eduQuantitative Profiling of DNA N6-methyladenine at single-base resolution with NAME-Seq
24SarahNealsjneal@mdanderson.orgA Baboon Research Resource for Use in Studies on Substance Abuse Disorders
25JulieWhitejdwhite@rti.orgIntegration of DNA methylation and RNA sequencing elucidates differential gene regulation associated with alcohol use disorder in the human brain
26AnastasiaWilliamsawill57@gmu.eduThe effects of cannabidiol and HU308 on viral transcription in HIV-1 infected cells and resulting extracellular vesicle release
27CarynWilliscdwillis@rti.orgGene Correlation Networks Replication Analysis Across Studies to Identify Top Candidate Gene Targets in Opioid Use Disorder Repurposing for the prevention of dementia among people living with human immunodeficiency virus: A focus on the renin-angiotensin system
29Rong-GuangXuroxu@bwh.harvard.eduHow histone post-translational modifications impact nucleosome structure and accessibility: A molecular dynamics study of psychedelic and epigenetic substances as novel approaches for treating substance addiction – hope or hype?
31ZhenyaoYezye@som.umaryland.eduPleiotropic genes for resting-state brain functional connectivity and nicotine addiction
32HangZhouhang.zhou@yale.eduMendelian Randomization Analysis of the Effects of Alcohol Use on Cancer Risk
33YanjiaoZhouyazhou@uchc.eduGenetic control of the microbiome and bile acids to influence addiction-related behaviors
34LauraHackhack@stanford.eduKetamine’s Acute Effects on Negative Brain States are Mediated through Distinct Altered States in Humans
35YanchaoPanhanyou@umich.eduA revamped rat reference genome improves the discovery of genetic diversity of laboratory rats
Abstracts From Those Unavailable to Present
First NameLast NameEmailAbstract Title
Li-ShiunChenli-shiun@wustl.eduRoadmap for translating genomic evidence to clinical interventions for prevention and treatment genetic risk factors for externalizing and internalizing alcohol use disorder behaviors through large-scale cross-disorder GWAS
DesmondSmithDSmith@mednet.ucla.eduCocaine and cannabis: a joint dependence revealed by a longitudinal genetic study in mice