Division of Therapeutics and Medical Consequences (DTMC)

What We Do:

  1. Plans and directs studies necessary to identify, evaluate, develop, and obtain FDA approval for new medications and devices to treat Substance Use Disorders (SUD) and related medical and psychiatric conditions;
  2. Develops and administers a program on basic and clinical research to (a) develop innovative  pharmacological and non-pharmacological approaches for SUDs and related medical and psychiatric conditions and (b) investigate the medical consequences of drug abuse, including HIV/AIDS;
  3. Supports research to identify valid and reliable outcome measures for clinical trials of therapeutics for SUDs;
  4. Supports training in the pre-clinical and clinical research of therapeutics for SUDs;
  5. Collaborates with: (a) the pharmaceutical sector in both the United States and abroad, and (b) other federal therapeutic development programs;
  6. Works closely with FDA in assuring that research designed to demonstrate the clinical efficacy of new compounds is evaluated and approved in an expeditious manner; and
  7. Disseminates the knowledge acquired by the DTMC funded research.

DTMC Pipelines of Therapeutics

Opioid Use Disorder and Overdose
Early PreclinicalLate PreclinicalPhase I Clinical TrialsPhase II Clinical TrialsNew Formulation

If you have questions, please contact Ivan Montoya or Marta de Santis

Stimulant Use Disorder and Overdose
Early PreclinicalLate PreclinicalClinical Trials
Phase IPhase IbPhase IIPhase III
 

If you have questions, please contact Katrina Foster or Ivan Montoya

Tobacco Use Disorder
Early PreclinicalLate PreclinicalClinical Trials
Phase IPhase IbPhase IIPhase III
  

If you have questions, please contact Evan Herrmann.

Cannabis Use Disorder
Early PreclinicalLate PreclinicalClinical Trials
Phase IPhase IIPhase III
 

If you have questions, please contact Aidan Hampson.

Research Programs:

Division Listings:

Funding Opportunities

Staff Listings:

Mailing Address:

Division of Therapeutics & Medical Consequences
National Institute on Drug Abuse
C/O NIH Mail Center
3WFN MSC 6016
16071 Industrial Drive – Dock 11
Gaithersburg, MD 20892*
*(Use 20892 for U.S. Postal Service, 20877 for UPS and FedEx)

(301) 443-6173 (phone)
(301) 443-2599 (fax)